2358University of Virginia, Charlottesville, VA, USA.
Neuroradiol J. 2023 Apr;36(2):232-235. doi: 10.1177/19714009221126015. Epub 2022 Sep 8.
2016 World Health Organization (WHO) Classification of Tumors of the Central Nervous System (CNS) has shown how molecular features can impact the classification of brain tumors. The continued combination of molecular features with histopathology has led to distinguish tumors with similar histopathologic features but distinct clinical prognosis. The 2021 revised 5. edition of the WHO classification further includes molecular features for CNS tumor categorization including altered diffuse astrocytoma which is a newly recognized type of low-grade pediatric-type brain tumor. We discuss imaging features of two pediatric-type low-grade gliomas with -mutation that encountered at our institution.
2016 年世界卫生组织（WHO）中枢神经系统（CNS）肿瘤分类显示了分子特征如何影响脑肿瘤的分类。分子特征与组织病理学的持续结合导致了具有相似组织病理学特征但不同临床预后的肿瘤的区分。2021 年 WHO 分类的第五版修订版进一步包括了 CNS 肿瘤分类的分子特征，包括改变的弥漫性星形细胞瘤，这是一种新认定的低级儿科脑肿瘤类型。我们讨论了在我们机构中遇到的两种具有 -突变的儿科型低级神经胶质瘤的影像学特征。
