Department of Urology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania;
Rom J Morphol Embryol. 2022 Jan-Mar;63(1):237-244. doi: 10.47162/RJME.63.1.27.
The pure retroperitoneal lipoma is a sporadic benign tumor originating from the mesenchymal tissue. There are only a few data in the literature. The technique available at this moment cannot establish a clear distinction between a benign adipose mass and a low-grade liposarcoma. This study presents the case of a 53-year-old man presenting computed tomography (CT) and magnetic resonance imaging (MRI) findings that revealed a giant retroperitoneal fatty tumor of 365∕210∕165 mm dimensions, suspected of malignancy. The patient's medical history, clinical data, and blood tests are more likely inclined to a benign condition. Liposarcoma couldn't be excluded preoperatively. The patient underwent an open surgical procedure respecting the oncological principles, with complete resection of 6400 g of retroperitoneal adipose tumor that also affected the surrounding organs' normal abdominal anatomy. The tumor was relatively well delimited without any signs of local invasion or infiltration. Three solid masses described on the MRI were identified upon dissection and sent separately for histological examination. The result indicated a giant retroperitoneal lipoma with benign characteristics. Facing imagistic difficulties to distinguish lipoma from liposarcoma clearly, and the inconclusiveness of fine-needle biopsies, oncological resection remains the only option as a diagnostic method and curative treatment.
单纯腹膜后脂肪瘤是一种起源于间叶组织的散发性良性肿瘤。文献中仅有少数数据。目前的技术尚无法明确区分良性脂肪肿块和低度脂肪肉瘤。本研究介绍了一名 53 岁男性的病例,其计算机断层扫描(CT)和磁共振成像(MRI)结果显示,腹膜后有一个 365∕210∕165 毫米大小的巨大腹膜后脂肪肿瘤,疑似恶性肿瘤。患者的病史、临床数据和血液检查更倾向于良性病变。术前不能排除脂肪肉瘤的可能。患者接受了开放手术,遵循肿瘤学原则,完整切除了 6400 克腹膜后脂肪肿瘤,该肿瘤还影响了周围器官的正常腹部解剖结构。肿瘤界限相对清晰,没有任何局部侵犯或浸润的迹象。在解剖过程中发现了三个在 MRI 上描述的实性肿块,并分别送检进行组织学检查。结果表明为良性特征的巨大腹膜后脂肪瘤。由于影像学难以明确区分脂肪瘤和脂肪肉瘤,细针活检结果不确定,因此,作为一种诊断方法和治疗方法,肿瘤切除仍然是唯一的选择。