Wang Ya-Rong, Wang Shan-Ze, Robert Kiltz, Zhao Ji-Ping
Department of Acupuncture and Moxibustion, Dongzhimen Hospital, Beijing University of CM, Beijing 100700, China.
Department of Acupuncture and Moxibustion, Second Affiliated Hospital of Guangzhou University of CM/Guangdong Provincial Hospital of TCM.
Zhongguo Zhen Jiu. 2022 Sep 12;42(9):987-90. doi: 10.13703/j.0255-2930.20210625-0005.
To observe the difference in the efficacy of acupuncture intervention at different time points on the pregnancy rate of in vitro fertilization-frozen embryo transfer (IVF-FET).
Ninety-nine patients with secondary infertility who were going to receive IVF-FET were divided into a transplantation-day acupuncture group, a transplantation cycle acupuncture group, and a non-acupuncture group according to their wishes, with 33 cases in each group. All three groups of patients received conventional IVF-FET treatment. The transplantation-day acupuncture group received acupuncture treatment 1 h before and 30 min after the embryo transfer, and the transplantation cycle acupuncture group received acupuncture treatment 5 weeks before the FET (once a week, 5 times) and on the day of transplantation, Zigong (EX-CA 1), Guanyuan (CV 4), Taichong (LR 3), Hegu (LI 4), etc. were selected in the two groups. The biochemical pregnancy rate and clinical pregnancy rate in the three groups were compared.
The biochemical pregnancy rate and clinical pregnancy rate in the transplantation cycle acupuncture group were higher than those in the non-acupuncture group (<0.05). There was no statistical difference in the biochemical pregnancy rate and clinical pregnancy rate between the transplantation cycle acupuncture group and the transplantation-day acupuncture group, and between the transplantation-day acupuncture group and the non-acupuncture group (>0.05).
Acupuncture during the transplantation cycle can effectively improve the pregnancy rate of secondary infertility patients receiving IVF-FET.
观察针刺干预在不同时间点对体外受精-冻融胚胎移植(IVF-FET)妊娠率的影响差异。
将99例拟行IVF-FET的继发性不孕患者按意愿分为移植日针刺组、移植周期针刺组和非针刺组,每组33例。三组患者均接受常规IVF-FET治疗。移植日针刺组在胚胎移植前1小时和移植后30分钟接受针刺治疗,移植周期针刺组在FET前5周(每周1次,共5次)及移植日接受针刺治疗,两组均选取子宫(EX-CA 1)、关元(CV 4)、太冲(LR 3)、合谷(LI 4)等穴位。比较三组的生化妊娠率和临床妊娠率。
移植周期针刺组的生化妊娠率和临床妊娠率高于非针刺组(<0.05)。移植周期针刺组与移植日针刺组之间、移植日针刺组与非针刺组之间的生化妊娠率和临床妊娠率比较,差异无统计学意义(>0.05)。
移植周期针刺可有效提高接受IVF-FET的继发性不孕患者的妊娠率。