Department of Pathology, Hospital Universitario Infanta Elena Valdemoro, Madrid, Spain.
Bioinformatics & Biostatistics Service, Biological Research Center - Spanish National Research Council (CIB-CSIC), Madrid, Spain.
Rev Esp Patol. 2022 Sep;55 Suppl 1:S27-S31. doi: 10.1016/j.patol.2020.02.008. Epub 2020 Mar 31.
Malignant pleural mesothelioma is a neoplasm involving mesothelial cells of the pleura. Both local and distant metastases may develop, although the latter are less common and it is extremely rare for cutaneous metastases to appear as a solitary lesion on the scalp. We present the case of a 54-year-old woman with a 2-year history of unresectable left pleural mesothelioma treated with chemotherapy, who had developed a painful lump on the scalp one month prior to consultation. Skin metastases of mesothelioma must be differentiated from primary neoplasms, and immunohistochemistry is fundamental to determine the origin of such lesions, which can be correctly identified through the use of a panel of markers.
恶性胸膜间皮瘤是一种涉及胸膜间皮细胞的肿瘤。可能发生局部和远处转移，尽管后者较少见，并且皮肤转移极为罕见地以头皮孤立性病变出现。我们报告了一例 54 岁女性病例，该女性患有 2 年不可切除的左侧胸膜间皮瘤，接受了化疗治疗，在就诊前一个月头皮上出现了一个疼痛的肿块。间皮瘤的皮肤转移必须与原发性肿瘤区分开来，免疫组织化学对于确定此类病变的起源至关重要，通过使用一组标志物可以正确识别这些病变。
