Department of Neurosurgery, All India Institute of Medical Sciences (AIIMS), Jodhpur, Rajasthan, India.
Department of Neurology, All India Institute of Medical Sciences (AIIMS), Jodhpur, Rajasthan, India.
Neurol India. 2022 Jul-Aug;70(4):1661-1664. doi: 10.4103/0028-3886.355121.
The cerebellum is classically linked with control of motor function, such as coordination, balance, and regulation of movement. There is an increasing awareness, now, of the non-motor functions of the cerebellum, and the occurrence of behavioral anomalies with cerebellar disorders. We present the first report of Schmahmann syndrome (cerebellar cognitive affective syndrome [CCAS]) occurring secondary to posterior fossa meningioma excision. A 35-year-old lady with a posterior fossa meningioma developed an infarct of the right posterosuperior cerebellar hemisphere and ipsilateral superior vermis, following suboccipital craniotomy and tumor resection. Few days after the surgery, she presented with aggressive and emotional behavior, irrelevant talk, and emotional lability. The CCAS scale was administered, and she scored poorly on almost all parameters. A neuropsychological evaluation was also done. The occurrence of CCAS, posterior fossa syndrome (PFS), and behavioral abnormalities like abnormal pathological laughter/crying provides further clinical evidence of the "affective" functions of the cerebellum, modulated mainly by the posterior lobe and vermis of the cerebellum.
小脑经典地与运动功能的控制相关，例如协调、平衡和运动的调节。现在，人们越来越意识到小脑的非运动功能，以及小脑疾病的行为异常的发生。我们首次报告了Schmahmann 综合征（小脑认知情感综合征[CCAS]）继发于后颅窝脑膜瘤切除。一位 35 岁的女性因后颅窝脑膜瘤行枕下开颅术和肿瘤切除术，导致右侧小脑上后叶和同侧上蚓部梗死。手术后几天，她表现出攻击性和情绪化行为、无关的谈话和情绪不稳定。进行了 CCAS 量表评估，她在几乎所有参数上的得分都很差。还进行了神经心理学评估。CCAS、后颅窝综合征（PFS）和异常病理性大笑/哭泣等行为异常的发生进一步提供了小脑的“情感”功能的临床证据，主要由小脑的后叶和蚓部调节。
