人类恶性肿瘤中12号染色体的倒位
Inversions of chromosome 12 in human malignancies.
作者信息
Larripa I, Mecucci C, Testoni N, Bosly A, Doyen C, Tytgat H, Van den Berghe H
出版信息
Cancer Genet Cytogenet. 1987 Sep;28(1):113-8. doi: 10.1016/0165-4608(87)90360-8.
PMID:3607733
Abstract
We present four cases with a malignant hematologic disorder and an inversion (peri- or paracentric) involving chromosome #12. Two cases of myelodysplastic syndrome showed an identical acquired pericentric inv(12)(p12q23). The pertinent literature on constitutional and acquired inversions of chromosome #12 has been revised.
摘要
我们报告了4例患有恶性血液系统疾病且涉及12号染色体倒位（臂间或近着丝粒）的病例。2例骨髓增生异常综合征表现出相同的后天性近着丝粒inv(12)(p12q23)。有关12号染色体先天性和后天性倒位的相关文献已得到修订。
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