Jiang Cuixia, Dong Quanmin, Xin Xiaoping, Degen Abraham Allan, Ding Luming
State Key Laboratory of Grassland Agro-ecosystem, College of Ecology, Lanzhou University, Lanzhou 730000, China.
Qinghai Provincial Key Laboratory of Adaptive Management on Alpine Grassland, Qinghai University, Xining 810016, China.
Animals (Basel). 2022 Aug 29;12(17):2228. doi: 10.3390/ani12172228.
Chinese traditional herbs are used widely as feed supplements to improve the immune response and antioxidant capacity of livestock. Twenty early-weaned 4-month-old yak calves (72.3 ± 3.65 kg) were divided randomly into four groups (n = 5 per group); three groups were provided with supplementary 80 mL/kg DMI of the root water extracts of either Angelica sinensis, Codonopsis pilosula or Glycyrrhiza uralensis, and one group (control) was not provided with a supplement. Compared to control calves, calves consuming the three herbal extracts increased serum concentrations of albumin (ALB) and glutathione peroxidase (GSH-Px), but decreased serum concentrations of free fatty acids (FFAs) and malondialdehyde (MDA) (p < 0.05). Calves consuming A. sinensis decreased (p < 0.05) serum concentration of total cholesterol (TC), and increased (p < 0.05) serum concentration of total proteins (TP). Serum FFA concentrations increased (p = 0.004) linearly with time in the control group, but not in the groups consuming herbs. Serum metabolomic data demonstrated that A. sinensis and C. pilosula regulate mainly amino acid metabolism, while G. uralensis regulates mainly carbon and amino acid metabolism. It was concluded that the three herbal root extracts, as dietary supplements, improved energy and nitrogen metabolism, and enhanced the antioxidant capacity of yak calves.
中国传统草药被广泛用作饲料添加剂，以提高家畜的免疫反应和抗氧化能力。将20头4月龄的早期断奶牦牛犊牛（体重72.3±3.65千克）随机分为四组（每组n = 5）；三组分别给予80毫升/千克干物质采食量的当归、党参或甘草根水提取物作为补充剂，一组（对照组）不给予补充剂。与对照犊牛相比，食用三种草药提取物的犊牛血清白蛋白（ALB）和谷胱甘肽过氧化物酶（GSH-Px）浓度升高，但血清游离脂肪酸（FFA）和丙二醛（MDA）浓度降低（p < 0.05）。食用当归的犊牛血清总胆固醇（TC）浓度降低（p < 0.05），血清总蛋白（TP）浓度升高（p < 0.05）。对照组血清FFA浓度随时间呈线性增加（p = 0.004），而食用草药的组则没有。血清代谢组学数据表明，当归和党参主要调节氨基酸代谢，而甘草主要调节碳和氨基酸代谢。得出的结论是，这三种草药根提取物作为膳食补充剂，改善了牦牛犊牛的能量和氮代谢，并增强了其抗氧化能力。
