Comparative Effectiveness and Safety of Concomitant Treatment with Chuna Manual Therapy and Usual Care for Whiplash Injuries: A Multicenter Randomized Controlled Trial.

OBJECTIVES

We aimed to compare the effectiveness and safety of Chuna manual therapy combined with usual care to those of usual care alone for treating whiplash injuries.

DESIGN

A two-arm, parallel, assessor-blinded, multicenter pragmatic randomized clinical trial.

SETTING

Three hospitals in Korea.

PARTICIPANTS

Overall, 132 participants between 19 and 70 years of age, involved in traffic accidents and treated at three hospitals in Korea, >2 but <13 weeks prior to enrollment, with neck pain consistent with whiplash-associated disorder grades I and II and a numeric rating scale score ≥5 were included.

INTERVENTIONS

Participants were equally and randomly allocated to the Chuna manual therapy and usual care ( = 66) or usual care ( = 66) groups and underwent corresponding treatment for three weeks.

PRIMARY AND SECONDARY OUTCOME MEASURES

The primary outcome was the number of days to achieve a 50% pain reduction. Secondary outcomes included areas under the 50% numeric rating scale reduction curve: pain, disability, quality of life, and safety.

RESULTS

The Chuna manual therapy + usual care group (23.31 ± 21.36 days; = 0.01) required significantly fewer days to achieve 50% pain reduction compared to the usual care group (50.41 ± 48.32 days; = 0.01). Regarding pain severity, functional index, and quality of life index, Chuna manual therapy and usual care were more effective than usual care alone. Safety was acceptable in both groups.

CONCLUSIONS

In patients with subacute whiplash injury, Chuna manual therapy showed a rapid rate of recovery, high effectiveness, and safety.