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2
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BMC Musculoskelet Disord. 2019 Apr 9;20(1):158. doi: 10.1186/s12891-019-2523-2.
3
The association between lumbar spine radiographic features and low back pain: a systematic review and meta-analysis.腰椎影像学特征与下腰痛的关系:系统评价和荟萃分析。
Semin Arthritis Rheum. 2015 Apr;44(5):571-585. doi: 10.1016/j.semarthrit.2014.10.006. Epub 2014 Dec 8.
4
Association of benign joint hypermobility with spinal segmental motion and its clinical implication in active young males.良性关节活动过度与脊柱节段运动的相关性及其在活跃年轻男性中的临床意义。
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Associations of body mass index and body height with low back pain in 829,791 adolescents.829791 名青少年的体质指数和身高与腰痛的关系。
Am J Epidemiol. 2013 Aug 15;178(4):603-9. doi: 10.1093/aje/kwt019. Epub 2013 May 19.
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症状性关节活动过度与腰痛相关:一项全国青少年队列研究。

Symptomatic Joint Hypermobility Is Associated with Low Back Pain: A National Adolescents Cohort Study.

作者信息

Hershkovich Oded, Gordon Barak, Derazne Estela, Tzur Dorit, Afek Arnon, Lotan Raphael

机构信息

Department of Orthopedic Surgery, Wolfson Medical Center, Ha-Lokhamim St 62, Holon 5822012, Israel.

Medical Corps, Israeli Defense Forces, Jerusalem 9112102, Israel.

出版信息

J Clin Med. 2022 Aug 30;11(17):5105. doi: 10.3390/jcm11175105.

DOI:10.3390/jcm11175105
PMID:36079031
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9456634/
Abstract

Background: Low back pain (LBP) is a widespread medical complaint affecting many people worldwide and costing billions. Studies suggest a link between LBP and joint hypermobility. This study aimed to examine the association between symptomatic joint hypermobility (SJH), LBP, and gender. Methods: Data were obtained from a medical database containing 17-year-old candidates’ records before recruitment into mandatory military service. According to the Regulations of Medical Fitness Determination, information on disability codes associated with LBP and SJH was retrieved. Results: According to this national survey, the prevalence of SJH is 0.11% (1355 cases out of 1,220,073 subjects). LBP was identified in 3.7% of the cohort (44,755 subjects). Subjects were further subdivided into LBP without objective findings (LBPWF) (3.5%) and LBP with objective findings (LBPOF) (0.2%). The association between SJH and LBP was examined: the Odds Ratio (OR) was 2.912 (p < 0.0001). The odds rations for LBPWF and LBPOF were further calculated to be 2.914 (p < 0.000) and 2.876 (p < 0.000), respectively. Subjects with SJH were almost three times more prone to LBPWF and LBPOF. Conclusion: SJH is strongly associated with LBP in young adults. Further pathophysiological research is needed.

摘要

背景

腰痛(LBP)是一种普遍的医学主诉,影响着全球许多人,造成数十亿美元的损失。研究表明腰痛与关节活动过度之间存在联系。本研究旨在探讨症状性关节活动过度(SJH)、腰痛和性别之间的关联。方法:数据来自一个医学数据库,该数据库包含17岁应征入伍前候选人的记录。根据《医学体能判定条例》,检索了与腰痛和症状性关节活动过度相关的残疾代码信息。结果:根据这项全国性调查,症状性关节活动过度的患病率为0.11%(1,220,073名受试者中有1355例)。在该队列中,3.7%的人被诊断为腰痛(44,755名受试者)。受试者进一步细分为无客观体征的腰痛(LBPWF)(3.5%)和有客观体征的腰痛(LBPOF)(0.2%)。研究了症状性关节活动过度与腰痛之间的关联:优势比(OR)为2.912(p < 0.0001)。LBPWF和LBPOF的优势比进一步计算分别为2.914(p < 0.000)和2.876(p < 0.000)。有症状性关节活动过度的受试者患LBPWF和LBPOF的可能性几乎是其他人的三倍。结论:在年轻人中,症状性关节活动过度与腰痛密切相关。需要进一步开展病理生理学研究。