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症状性关节活动过度与腰痛相关:一项全国青少年队列研究。

Symptomatic Joint Hypermobility Is Associated with Low Back Pain: A National Adolescents Cohort Study.

作者信息

Hershkovich Oded, Gordon Barak, Derazne Estela, Tzur Dorit, Afek Arnon, Lotan Raphael

机构信息

Department of Orthopedic Surgery, Wolfson Medical Center, Ha-Lokhamim St 62, Holon 5822012, Israel.

Medical Corps, Israeli Defense Forces, Jerusalem 9112102, Israel.

出版信息

J Clin Med. 2022 Aug 30;11(17):5105. doi: 10.3390/jcm11175105.

Abstract

Background: Low back pain (LBP) is a widespread medical complaint affecting many people worldwide and costing billions. Studies suggest a link between LBP and joint hypermobility. This study aimed to examine the association between symptomatic joint hypermobility (SJH), LBP, and gender. Methods: Data were obtained from a medical database containing 17-year-old candidates’ records before recruitment into mandatory military service. According to the Regulations of Medical Fitness Determination, information on disability codes associated with LBP and SJH was retrieved. Results: According to this national survey, the prevalence of SJH is 0.11% (1355 cases out of 1,220,073 subjects). LBP was identified in 3.7% of the cohort (44,755 subjects). Subjects were further subdivided into LBP without objective findings (LBPWF) (3.5%) and LBP with objective findings (LBPOF) (0.2%). The association between SJH and LBP was examined: the Odds Ratio (OR) was 2.912 (p < 0.0001). The odds rations for LBPWF and LBPOF were further calculated to be 2.914 (p < 0.000) and 2.876 (p < 0.000), respectively. Subjects with SJH were almost three times more prone to LBPWF and LBPOF. Conclusion: SJH is strongly associated with LBP in young adults. Further pathophysiological research is needed.

摘要

背景

腰痛(LBP)是一种普遍的医学主诉,影响着全球许多人,造成数十亿美元的损失。研究表明腰痛与关节活动过度之间存在联系。本研究旨在探讨症状性关节活动过度(SJH)、腰痛和性别之间的关联。方法:数据来自一个医学数据库,该数据库包含17岁应征入伍前候选人的记录。根据《医学体能判定条例》,检索了与腰痛和症状性关节活动过度相关的残疾代码信息。结果:根据这项全国性调查,症状性关节活动过度的患病率为0.11%(1,220,073名受试者中有1355例)。在该队列中,3.7%的人被诊断为腰痛(44,755名受试者)。受试者进一步细分为无客观体征的腰痛(LBPWF)(3.5%)和有客观体征的腰痛(LBPOF)(0.2%)。研究了症状性关节活动过度与腰痛之间的关联:优势比(OR)为2.912(p < 0.0001)。LBPWF和LBPOF的优势比进一步计算分别为2.914(p < 0.000)和2.876(p < 0.000)。有症状性关节活动过度的受试者患LBPWF和LBPOF的可能性几乎是其他人的三倍。结论:在年轻人中,症状性关节活动过度与腰痛密切相关。需要进一步开展病理生理学研究。

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