Department of Community and Family Medicine, Duke University, Durham, NC 27713, USA.
Curr Rheumatol Rep. 2013 Feb;15(2):305. doi: 10.1007/s11926-012-0305-z.
Lumbar spine osteoarthritis (OA) is very common, with estimates of prevalence ranging from 40-85 %. The process of degeneration of the spine has commonly been classified as OA (disc space narrowing together with vertebral osteophyte formation); however, anatomically, the facet joint is the only synovial joint in the spine that has a similar pathological degenerative process to appendicular joints. Low back pain (LBP) is also a common condition, with nearly 80 % of Americans experiencing at least one episode of LBP in their lifetime. The complex relationship between spine radiographs and LBP has many clinical and research challenges. Specific conservative treatments for spine degeneration have not been established; there has, however, been recent interest in use of exercise therapy, because of some moderate benefits in treating chronic LBP. An understanding of the relationship between spine degeneration and LBP may be improved with further population-based research in the areas of genetics, biomarkers, and pain pathways.
腰椎骨关节炎(OA)非常常见,其患病率估计范围为 40-85%。脊柱退化过程通常被归类为 OA(椎间盘间隙变窄伴椎体骨赘形成);然而,从解剖学上讲,关节突关节是脊柱中唯一具有类似关节附加物退行性病理过程的滑膜关节。下腰痛(LBP)也是一种常见病症,近 80%的美国人在其一生中至少经历过一次 LBP。脊柱 X 线片与 LBP 之间的复杂关系存在许多临床和研究挑战。尚未确定针对脊柱退变的具体保守治疗方法;然而,由于运动疗法对慢性 LBP 的一些适度益处,最近人们对其产生了兴趣。通过在遗传、生物标志物和疼痛途径等领域进行更多的基于人群的研究,可能会更好地了解脊柱退变与 LBP 之间的关系。