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奥密克戎变异株感染住院的COVID-19患者再次入院情况——一项回顾性队列研究

Re-Admission of COVID-19 Patients Hospitalized with Omicron Variant-A Retrospective Cohort Study.

作者信息

Ayalon-Dangur Irit, Turjeman Adi, Basharim Bar, Bigman-Peer Noa, Magid Einat, Green Hefziba, Shochat Tzippy, Grossman Alon, Bishara Jihad, Eliakim-Raz Noa

机构信息

Internal Medicine E, Rabin Medical Center, Beilinson Hospital, Petah Tikva 49100, Israel.

Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.

出版信息

J Clin Med. 2022 Sep 2;11(17):5202. doi: 10.3390/jcm11175202.

DOI:10.3390/jcm11175202
PMID:36079138
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9457250/
Abstract

In accordance with previous publications, re-admission rates following hospitalization of patients with COVID-19 is 10%. The aim of the current study was to describe the rates and risk factors of hospital re-admissions two months following discharge from hospitalization during the fifth wave due to the dominant Omicron variant. A retrospective cohort study was performed in Rabin Medical Center, Israel, from November 2021 to February 2022. The primary outcome was re-admissions with any diagnosis; the secondary outcome was mortality within two months of discharge. Overall, 660 patients were hospitalized with a diagnosis of COVID-19. Of the 528 patients discharged from a primary hospitalization, 150 (28%) were re-admitted. A total of 164 patients (25%) died throughout the follow-up period. A multi-variable analysis determined that elevated creatinine was associated with a higher risk of re-admissions. Rates of re-admissions after discharge during the Omicron wave were considerably higher compared to previous waves. A discharge plan for surveillance and treatment following hospitalization is of great importance in the management of pandemics.

摘要

根据先前的出版物,新冠病毒疾病(COVID-19)患者住院后的再入院率为10%。本研究的目的是描述在第五波疫情期间,由于占主导地位的奥密克戎变种导致患者出院两个月后再次入院的比率及风险因素。2021年11月至2022年2月,在以色列拉宾医疗中心进行了一项回顾性队列研究。主要结局是再次入院时的任何诊断;次要结局是出院后两个月内的死亡率。总体而言,660例患者因诊断为COVID-19而住院。在528例初次住院出院的患者中,150例(28%)再次入院。在整个随访期间,共有164例患者(25%)死亡。多变量分析确定,肌酐升高与再次入院风险较高相关。与之前的疫情波相比,奥密克戎疫情波期间出院后的再入院率要高得多。住院后的监测和治疗出院计划在大流行管理中非常重要。

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