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[肿瘤标志物在甲状腺癌监测中的应用]

[Use of tumor markers in monitoring thyroid carcinoma].

作者信息

Gorgone S, Lazzara S, Palmeri R, Belnome N, Calbo L, Dattola P, Melita P

出版信息

Chir Ital. 1987 Feb;39(1):87-95.

PMID:3607983
Abstract

The authors report on their experience regarding the use of tumours markers for the pre-operative monitoring and subsequent follow-up of patients suffering from thyroid carcinoma. All patients were subjected to radio-immuno-assay for circulating thyroglobulin, a valuable indicator of residual and metastatic thyroid tissue. The patients suffering from medullary carcinoma of the thyroid and their immediate families were also monitored by periodic thyrocalcitonin assay. A further tumour marker assayed was CEA, levels of which are raised in the presence of thyroid neoplasms at an advanced or metastasizing stage. The authors conclude by presenting the results obtained and confirm the usefulness of these tumour markers in the study and follow-up of patients with thyroid carcinoma.

摘要

作者报告了他们使用肿瘤标志物对甲状腺癌患者进行术前监测及后续随访的经验。所有患者均接受循环甲状腺球蛋白的放射免疫测定,甲状腺球蛋白是残留及转移性甲状腺组织的一项重要指标。甲状腺髓样癌患者及其直系亲属也通过定期测定降钙素进行监测。另一项检测的肿瘤标志物是癌胚抗原(CEA),在甲状腺肿瘤处于晚期或发生转移时其水平会升高。作者通过展示所获得的结果得出结论,并证实了这些肿瘤标志物在甲状腺癌患者研究及随访中的有用性。

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