Department of Systems Medicine, University of Rome Tor Vergata, 00133 Rome, Italy.
Obesity Medical Center, Policlinico Tor Vergata, 00133 Rome, Italy.
Nutrients. 2022 Aug 31;14(17):3610. doi: 10.3390/nu14173610.
Bariatric surgery (BS) is the most effective treatment in reducing weight and the burden of comorbidities in patients with severe obesity. Despite the overall low mortality rate, intra- and post-operative complications remains quite common. Weight loss before BS reduces surgical risk, but studies are inconclusive regarding which is the best approach to apply. In this review, we summarize the current evidence on the effect of a ketogenic diet (KD) before BS. All studies agree that KD leads to considerable weight loss and important improvements in terms of surgical risk, but populations, interventions and outcomes are very heterogeneous. KD appears to be a safe and effective approach to induce weight loss before BS. However, randomized controlled trials with better-defined dietary protocols and homogeneous outcomes are necessary in order to draw firm conclusions.
减重手术(BS)是治疗重度肥胖患者减轻体重和并发症负担最有效的方法。尽管总体死亡率较低,但围手术期并发症仍然很常见。BS 前的体重减轻可以降低手术风险,但关于哪种方法是最佳的应用方法,研究结果尚无定论。在这篇综述中,我们总结了 BS 前酮饮食(KD)的效果的现有证据。所有研究都认为 KD 可导致显著的体重减轻,并显著改善手术风险,但人群、干预措施和结果非常多样。KD 似乎是一种安全有效的方法,可以在 BS 前诱导体重减轻。然而,为了得出更确切的结论,需要进行具有更好定义的饮食方案和同质结果的随机对照试验。