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地中海饮食与心房颤动：来自 AFHRI 病例对照研究的经验教训。

Mediterranean Diet and Atrial Fibrillation: Lessons Learned from the AFHRI Case-Control Study.

机构信息

Preventive Medicine and Nutrition, Midwifery Science - Health Services Research and Prevention, Institute for Health Services Research in Dermatology and Nursing (IVDP), University Medical Center Hamburg-Eppendorf (UKE), 20246 Hamburg, Germany.

German Center for Cardiovascular Research (DZHK), Partner site Hamburg/Kiel/Lübeck, 20246 Hamburg, Germany.

出版信息

Nutrients. 2022 Sep 1;14(17):3615. doi: 10.3390/nu14173615.

DOI:10.3390/nu14173615
PMID:36079872
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9459737/
Abstract

A relationship between lifestyle, diet, and atrial fibrillation (AF) remains unclear. Except for alcohol consumption, AF guidelines do not differentiate specific advice for this rhythm disorder. The aim of this study was to investigate the association between adherence to healthy dietary patterns and the presence of AF, among 104 low risk participants from the 1:1 matched case-control AFHRI (Atrial Fibrillation in High-Risk Individuals) study. Dietary data were obtained using a three-day food record. Adapted German versions of the validated 14-item Mediterranean Diet Adherence Screener (MEDAS) and the validated eight-item Healthy Eating Index (HEI) from the Epic Study served as the basis for data derivation. The median age of the study participants was 63.0 years, 73.1% were men. In multivariable adjusted binary logistic regression analyses, we found inverse associations between both dietary indices (MEDAS: Median = 3, HEI: Median = 54.9) and the presence of AF (odds ratio for MEDAS: 0.65, 95% confidence interval (CI): 0.47-0.91, odds ratio for HEI: 0.60, 95% CI 0.39-0.95). Further clinical studies are needed to confirm the extent to which high quality dietary patterns such as a Mediterranean diet influence the onset and natural history of AF, in order to provide dietary counselling.

摘要

生活方式、饮食与心房颤动（AF）之间的关系仍不清楚。除了饮酒之外，AF 指南并没有针对这种节律紊乱提供具体的建议。本研究旨在调查在 104 名来自 1:1 匹配病例对照 AFHRI（高危人群中的心房颤动）研究的低危参与者中，健康饮食模式与 AF 之间的关系。通过三天的食物记录来获取饮食数据。采用经过验证的 14 项地中海饮食依从性筛查器（MEDAS）和来自 Epic 研究的经过验证的 8 项健康饮食指数（HEI）的德国改编版本作为数据推导的基础。研究参与者的中位年龄为 63.0 岁，73.1%为男性。在多变量调整的二元逻辑回归分析中，我们发现这两个饮食指数（MEDAS：中位数=3，HEI：中位数=54.9）与 AF 的存在呈负相关（MEDAS 的比值比：0.65，95%置信区间（CI）：0.47-0.91，HEI 的比值比：0.60，95% CI 0.39-0.95）。需要进一步的临床研究来确认高质量的饮食模式（如地中海饮食）在多大程度上影响 AF 的发生和自然史，以便提供饮食建议。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcd4/9459737/88619f6e344c/nutrients-14-03615-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcd4/9459737/1c95c950530c/nutrients-14-03615-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcd4/9459737/718b6e1cb593/nutrients-14-03615-g002.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcd4/9459737/97413055cfbd/nutrients-14-03615-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcd4/9459737/88619f6e344c/nutrients-14-03615-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcd4/9459737/1c95c950530c/nutrients-14-03615-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcd4/9459737/718b6e1cb593/nutrients-14-03615-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcd4/9459737/d0442f6e9c1c/nutrients-14-03615-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcd4/9459737/97413055cfbd/nutrients-14-03615-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcd4/9459737/88619f6e344c/nutrients-14-03615-g005.jpg

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