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地中海饮食筛查评分的适应性和预测能力。

Adaptation and predictive utility of a Mediterranean diet screener score.

机构信息

Cardiovascular Epidemiology Unit, Gertner Institute for Epidemiology and Health Policy Research, Ramat Gan 52621, Israel.

Nutrition Division, Ministry of Health, Jerusalem, Israel; School of Public Health, University of Haifa, Haifa 3498838, Israel.

出版信息

Clin Nutr. 2019 Dec;38(6):2928-2935. doi: 10.1016/j.clnu.2018.12.034. Epub 2019 Jan 5.

Abstract

BACKGROUND & AIMS: There is a substantial body of evidence supporting the health benefits of the Mediterranean diet, which has differing variations across the Mediterranean region. Abbreviated dietary screeners can be adapted and used to assess adherence to the local Mediterranean diet variant. We aimed to describe the process of adapting the Spanish Mediterranean Diet Adherence Screener (MEDAS) for use in Israel, and to test the predictive utility of the adapted score for mortality.

METHODS

A professional committee of nutritional policy makers, dieticians and researchers adapted MEDAS to create an Israeli Mediterranean diet screener (I-MEDAS) that reflected the local Mediterranean diet and national dietary recommendations. The Hadera District Study (HDS) was a population-based, prospective cohort study of adults in Israel. Food frequency questionnaire (FFQ) data from the HDS was used to calculate Mediterranean diet adherence according to the I-MEDAS score criteria and evaluate the score's predictive utility. Mortality status was obtained from the national population registry. Cox proportional hazards regression models were used to test the predictive utility of the I-MEDAS score for all-cause mortality.

RESULTS

The 14-item MEDAS was adapted to create a 17-item I-MEDAS. According to FFQ data from the HDS cohort (n = 1092 adults; median [IQR] follow-up time = 14 [12-15] years, 179 deaths), the median (IQR) I-MEDAS score was 8 (7-9). In multivariable analysis, every 1-point increase in the I-MEDAS score reduced the hazard of death by 12% (adjusted HR: 0.88; 95% CI: 0.80-0.97). The original MEDAS score was less strongly associated with mortality, and lost significance after adjustment for potential confounders.

CONCLUSIONS

I-MEDAS reflects the local Mediterranean diet and national dietary recommendations in Israel. The I-MEDAS score, calculated from FFQ data, demonstrated predictive utility for mortality in a population-based cohort of adults.

摘要

背景与目的

有大量证据支持地中海饮食对健康的益处,而地中海饮食在整个地中海地区存在不同的变化。简短的饮食筛查器可以进行改编并用于评估对当地地中海饮食变体的遵守情况。我们旨在描述改编西班牙地中海饮食依从性筛查器(MEDAS)以用于以色列的过程,并测试改编后的评分对死亡率的预测效用。

方法

一个由营养政策制定者、营养师和研究人员组成的专业委员会改编了 MEDAS,创建了一个反映当地地中海饮食和国家饮食建议的以色列地中海饮食筛查器(I-MEDAS)。Hadera 区研究(HDS)是以色列一项基于人群的前瞻性队列研究。使用来自 HDS 的食物频率问卷(FFQ)数据,根据 I-MEDAS 评分标准计算地中海饮食依从性,并评估该评分的预测效用。死亡率状态从国家人口登记处获得。使用 Cox 比例风险回归模型测试 I-MEDAS 评分对全因死亡率的预测效用。

结果

14 项 MEDAS 改编为 17 项 I-MEDAS。根据 HDS 队列的 FFQ 数据(n=1092 名成年人;中位数[IQR]随访时间=14[12-15]年,179 人死亡),I-MEDAS 评分中位数(IQR)为 8(7-9)。在多变量分析中,I-MEDAS 评分每增加 1 分,死亡风险降低 12%(调整后的 HR:0.88;95%CI:0.80-0.97)。原始 MEDAS 评分与死亡率的相关性较弱,并且在调整潜在混杂因素后失去了意义。

结论

I-MEDAS 反映了以色列当地的地中海饮食和国家饮食建议。从 FFQ 数据计算得出的 I-MEDAS 评分,在基于人群的成年人队列中对死亡率具有预测效用。

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