Bundang CHA Medical Center, Department of Otorhinolaryngology-Head and Neck Surgery, CHA University, Seongnam 13488, Korea.
Hallym Data Science Laboratory, Hallym University College of Medicine, Anyang 14066, Korea.
Nutrients. 2022 Sep 4;14(17):3655. doi: 10.3390/nu14173655.
The present study aimed to investigate the coincidence of obesity and nutritional intake in monozygotic twins compared to dizygotic twins. The data from the Korean Genome and Epidemiology Study (KoGES) from 2005 through 2014 were analyzed. Participants ≥ 20 years old were enrolled. The 1006 monozygotic twins and 238 dizygotic twins were analyzed for differences in self-reported nutritional intake, total body fat, and body mass index (BMI) using a linear regression model. The estimated values (EV) with 95% confidence intervals (95% CI) of the difference in dietary intake, total body fat, and BMI score were calculated. The monozygotic twin group and the dizygotic twin group showed similar differences in nutritional intake, DEXA fat, and BMI (all p > 0.05). The differences in nutritional intake of total calories and carbohydrates were lower in the monozygotic twin group than in the dizygotic twin group (all p < 0.05). The differences in total body fat were lower in monozygotic twins than in dizygotic twins (adjusted EV = 2427.86 g, 95% CI = 1777.19−3078.53 and adjusted EV = 1.90%, 95% CI = 1.33−2.46). Monozygotic twins had more similar dietary habits for total calories and carbohydrate intake. Other nutritional factors did not show differential similarity between monozygotic and dizygotic twins. Total body fat was more concordant in monozygotic twins.
本研究旨在比较同卵双胞胎和异卵双胞胎中肥胖与营养摄入的一致性。分析了 2005 年至 2014 年韩国基因组和流行病学研究（KoGES）的数据。纳入年龄≥20 岁的参与者。使用线性回归模型分析了 1006 对同卵双胞胎和 238 对异卵双胞胎的自我报告营养摄入、总体体脂肪和体重指数（BMI）差异。计算了膳食摄入、DEXA 脂肪和 BMI 评分差异的估计值（EV）及其 95%置信区间（95%CI）。同卵双胞胎组和异卵双胞胎组在营养摄入、DEXA 脂肪和 BMI 方面的差异相似（均 P>0.05）。同卵双胞胎组的总热量和碳水化合物的营养摄入差异低于异卵双胞胎组（均 P<0.05）。同卵双胞胎的总体脂肪差异低于异卵双胞胎（调整后的 EV=2427.86g，95%CI=1777.19−3078.53 和调整后的 EV=1.90%，95%CI=1.33−2.46）。同卵双胞胎的总热量和碳水化合物摄入的饮食习惯更相似。其他营养因素在同卵和异卵双胞胎之间没有表现出差异的相似性。同卵双胞胎的总体脂肪更一致。
