The Key Laboratory of Microbiology and Parasitology of Anhui Province, The Key Laboratory of Zoonoses of High Institutions in Anhui, Department of Pathogen Biology, School of Basic Medical Sciences, Anhui Medical University, Hefei 230032, China.
Molecules. 2022 Aug 28;27(17):5534. doi: 10.3390/molecules27175534.
As a prevention tool for mosquito-borne diseases, mosquito repellents have received substantial attention. To make a convincing recommendation for repellent products to Chinese consumers, we compared the protection time (landing time and probing time) of the 26 best-selling commercial repellents in the Chinese market in a controlled laboratory environment. The data were analyzed by one-way ANOVA. Meanwhile, prices and favorable rates of repellents are also taken into consideration. In our study, N, N-diethyl-m-toluamide (DEET)-based products provided the longest protection time (0.5-3.88 h landing time and/or 1-5.63 h probing time) and lower prices (13.9-21.9 yuan) than other components (ethyl butylacetylaminopropionate (IR3535), picaridin, and botanical. Among the 26 selected products, only 17 repellents showed repellency, and the best repellent was Green Jungle (15% DEET), with a mean (±SD) landing and/or probing time of 3.88 ± 1.65 h and/or 5.63 ± 0.36 h. For botanicals, only ICE King, OMNIbaby, and Ren He showed a little repellency. Autan (20% picaridin) performed best in the picaridin group. Run Ben (7% IR3535) stood out from the IR3535 group. In conclusion, DEET repellent is highly recommended to consumers. The combination of botanicals and synthesized chemicals is a new prospect for eco-friendly repellents.
作为预防蚊虫传播疾病的工具，驱蚊剂受到了广泛关注。为了向中国消费者推荐有说服力的驱蚊产品，我们在控制的实验室环境中比较了中国市场上 26 种最畅销的商业驱蚊剂的保护时间（停留时间和探测时间）。采用单因素方差分析对数据进行分析。同时，还考虑了驱蚊剂的价格和优惠率。在我们的研究中，N，N-二乙基间甲苯酰胺（DEET）基产品提供了最长的保护时间（0.5-3.88 小时停留时间和/或 1-5.63 小时探测时间）和较低的价格（13.9-21.9 元），优于其他成分（乙基丁基乙酰氨基丙酸盐（IR3535）、派卡瑞丁和植物性。在选择的 26 种产品中，只有 17 种驱蚊剂具有驱蚊效果，最好的驱蚊剂是绿丛林（15% DEET），平均（±SD）停留和/或探测时间为 3.88 ± 1.65 小时和/或 5.63 ± 0.36 小时。对于植物性，只有 ICE King、OMNIbaby 和仁和显示出一点驱蚊效果。派卡瑞丁组中 Autan（20%派卡瑞丁）表现最佳。IR3535 组中的润本（7%IR3535）表现出色。总之，强烈推荐 DEET 驱蚊剂给消费者。植物性和合成化学品的组合是环保型驱蚊剂的新前景。
