Parris W C
Can J Anaesth. 1987 Jul;34(4):403-6. doi: 10.1007/BF03010144.
Chronic headaches are difficult problems to manage effectively. A select group of six patients with headache symptoms (throbbing headaches, located in the frontal or occipital areas; aggravated by ambulation and relieved by recumbency) resembling post-dural puncture headache received epidural blood patches using autologous blood for their chronic headaches. Five of the six patients obtained effective and sustained pain relief. All of the patients had received placebo injections with normal saline in the paraspinous muscles, without effect. The mechanism of action of the blood patch in these patients is unclear. It is possible that the headache may have been caused by a low pressure cerebrospinal fluid state, due to an unknown anatomical or physiological defect of the ventriculo-spinal system. Further studies are needed to evaluate this treatment modality.
慢性头痛是难以有效管理的难题。一组特定的六名有头痛症状（搏动性头痛，位于额部或枕部区域；行走时加重，卧位时缓解）类似于硬膜穿刺后头痛的患者，接受了自体血硬膜外血贴治疗慢性头痛。六名患者中有五名获得了有效且持续的疼痛缓解。所有患者均接受过椎旁肌肉注射生理盐水的安慰剂治疗，但无效。血贴在这些患者中的作用机制尚不清楚。头痛可能是由于脑室 - 脊髓系统未知的解剖或生理缺陷导致脑脊液低压状态引起的。需要进一步研究来评估这种治疗方式。
