Antibacterial and antibiofilm activity of Lactobacillus strains secretome and extraction against isolated from urinary tract infection.

The purpose of this study was to antibacterial, and antibiofilm activity of two Lactobacillus strains secretome and extraction against isolated from women with urinary tract infection (UTI). We isolated 100 samples from women with UTI. and characteristics were evaluated, and their secretome and extraction were prepared. The antibacterial and antibiofilm activity of secretome and extraction of both Lactobacillus strains were evaluated against isolated samples. and were able to tolerate pH 3, bile salts, and pancreatic enzymes. Both probiotics were not resistant to antibiotics and demonstrated an appropriate ability to adhere to the intestinal epithelial cells. Secretome and extraction of and strains showed a good antibacterial and antibiofilm against isolates. Generally, present study suggested that the secretome and extraction of and strains exhibits a good antimicrobial activity.