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慢性肾脏病患者医院感染的相关因素与经济负担评估

Related Factors and Economic Burden Evaluation of Nosocomial Infection in Patients with Chronic Kidney Disease.

机构信息

School of Public Health, Capital Medical University, Beijing, China.

Hospital Infection Control Division, Shijingshan Teaching Hospital of Capital Medical University, Beijing Shijingshan Hospital, Beijing, China.

出版信息

Contrast Media Mol Imaging. 2022 Aug 24;2022:9889917. doi: 10.1155/2022/9889917. eCollection 2022.

Abstract

Kidney disease in China has the characteristics of "three highs and one low", namely high incidence, high disability rate, high treatment cost and low awareness. The main outcome is a progressive deterioration of renal function that is not easily corrected, and patients are often hospitalized repeatedly due to factors such as infection, fatigue, lack of medication, water and electrolyte imbalances. It not only accelerates the deterioration of renal function, but also easily causes psychological problems and seriously affects the quality of life of patients. Kidney is an organ with dual functions of endocrine and material metabolism in the human body, and plays an important role in both physiological and pathological processes. Its main functions include urine generation, renal tubular reabsorption, regulation of water and electrolyte metabolism, and endocrine functions. Chronic kidney disease is defined by an unexplained decrease in GFR over three months. At present, clinicians usually take drug corrective measures only when CKD patients have intermediate and advanced PEM with abnormal index examinations (such as decreased plasma albumin, anemia, etc.), and the clinical efficacy is not stable. At present, there are few studies on the related factors and economic burden of nosocomial infection in patients with chronic kidney disease. This study understands the nutrient intake of patients in each disease process, and makes individualized nutritional dietary guidance programs more targeted. Starting from the second day of the patient's hospitalization, the food eaten by the patient was weighed by professionals using the weighing method for 3 consecutive days. By recording and entering into the analysis system, it performs the calculation and analysis of food composition and nutrient intake, and analyzes it using statistical methods. The experimental results showed that patients aged 31-60 years had a higher risk of preoperative infection.

摘要

中国的肾脏病具有“三高三低”的特点,即发病率高、致残率高、治疗费用高、知晓率低。主要结局是肾功能进行性恶化,不易纠正,患者常因感染、疲劳、药物缺乏、水电解质失衡等因素反复住院。这不仅加速了肾功能的恶化,而且容易导致心理问题,严重影响患者的生活质量。肾脏是人体具有内分泌和物质代谢双重功能的器官,在生理和病理过程中都起着重要的作用。其主要功能包括尿液生成、肾小管重吸收、水和电解质代谢调节以及内分泌功能。慢性肾脏病是指 GFR 不明原因下降超过三个月。目前,临床医生通常只在 CKD 患者出现中间和晚期 PEM 且指标检查异常(如血浆白蛋白降低、贫血等)时才采取药物矫正措施,且临床疗效不稳定。目前,关于慢性肾脏病患者医院感染的相关因素和经济负担的研究较少。本研究了解了每位患者在不同病程中的营养摄入情况,使个体化营养饮食指导方案更具针对性。从患者住院的第二天开始,专业人员使用称重法连续 3 天对患者所吃的食物进行称重。通过记录并输入分析系统,对食物成分和营养摄入进行计算和分析,并使用统计方法进行分析。实验结果表明,年龄在 31-60 岁的患者术前感染风险较高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e3d/9433206/96c44daf7d9c/CMMI2022-9889917.001.jpg

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