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原发性雷诺现象患者注射利多卡因加肾上腺素后出现手指缺血。

Digital ischemia after lidocaine with epinephrine injection in a patient with primary Raynaud's phenomena.

作者信息

McNamara Colin T, Greyson Mark

机构信息

Division of Plastic and Reconstructive Surgery, University of Colorado Anschutz Medical Center, Aurora, CO, USA.

出版信息

Case Reports Plast Surg Hand Surg. 2022 Sep 4;9(1):193-196. doi: 10.1080/23320885.2022.2117702. eCollection 2022.

DOI:10.1080/23320885.2022.2117702
PMID:36082186
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9448404/
Abstract

Lidocaine with epinephrine is ubiquitous in hand procedures. Although existing literature supports the overall safety of this, significant physiologic changes accompanying epinephrine can disproportionately affect vascularly compromised patients, such as in Raynaud's phenomenon. The literature is reviewed and a case presented regarding the dangers of epinephrine injection in this population.

摘要

利多卡因加肾上腺素在手外科手术中广泛使用。尽管现有文献支持其总体安全性，但肾上腺素引起的显著生理变化可能对血管受损患者产生不成比例的影响，比如在雷诺现象患者中。本文回顾了相关文献，并呈现了一个关于在这类人群中注射肾上腺素危险性的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5870/9448404/cc6edbab8cff/ICRP_A_2117702_F0003_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5870/9448404/64727c291709/ICRP_A_2117702_F0001_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5870/9448404/be46bc4873a6/ICRP_A_2117702_F0002_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5870/9448404/cc6edbab8cff/ICRP_A_2117702_F0003_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5870/9448404/64727c291709/ICRP_A_2117702_F0001_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5870/9448404/be46bc4873a6/ICRP_A_2117702_F0002_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5870/9448404/cc6edbab8cff/ICRP_A_2117702_F0003_C.jpg

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Digital ischemia after lidocaine with epinephrine injection in a patient with primary Raynaud's phenomena.原发性雷诺现象患者注射利多卡因加肾上腺素后出现手指缺血。
Case Reports Plast Surg Hand Surg. 2022 Sep 4;9(1):193-196. doi: 10.1080/23320885.2022.2117702. eCollection 2022.
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本文引用的文献

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Safety of DIEP Flap Reconstruction in Patients with Factor V Leiden: A Retrospective Cohort Study.携带因子V莱顿突变患者行腹壁下动脉穿支皮瓣重建术的安全性：一项回顾性队列研究。
Plast Reconstr Surg Glob Open. 2022 Apr 25;10(4):e4244. doi: 10.1097/GOX.0000000000004244. eCollection 2022 Apr.
2
WALANT-Epinephrine injection may lead to short term, reversible episodes of critical oxygen saturation in the fingertips.WALANT-肾上腺素注射液可能导致指尖短期、可逆的临界血氧饱和度事件。
Arch Orthop Trauma Surg. 2021 Mar;141(3):527-533. doi: 10.1007/s00402-020-03744-5. Epub 2021 Jan 23.
3
The early history of adrenaline.
Anaesth Intensive Care. 2017 May;45(3):279-281. doi: 10.1177/0310057X1704500301.
4
Delayed-Onset Digital Ischemia After Local Anesthetic With Epinephrine Injection Requiring Phentolamine Reversal.肾上腺素注射局部麻醉后发生延迟性手指缺血，需用酚妥拉明逆转。
J Hand Surg Am. 2017 Jun;42(6):479.e1-479.e4. doi: 10.1016/j.jhsa.2017.01.006. Epub 2017 Mar 1.
5
Digital Necrosis After Lidocaine and Epinephrine Injection in the Flexor Tendon Sheath Without Phentolamine Rescue.在屈肌腱鞘内注射利多卡因和肾上腺素后未用酚妥拉明解救导致的手指坏死
J Hand Surg Am. 2017 Feb;42(2):e119-e123. doi: 10.1016/j.jhsa.2016.10.015. Epub 2016 Dec 10.
6
Post-traumatic Digital Gangrene Associated with Epinephrine Use in Primary Raynaud's Phenomenon: Lesson for the Future.原发性雷诺现象中与肾上腺素使用相关的创伤后手指坏疽：对未来的启示。
Ethiop J Health Sci. 2016 Jul;26(4):401-4. doi: 10.4314/ejhs.v26i4.13.
7
Raynaud's Phenomenon.雷诺现象
N Engl J Med. 2016 Aug 11;375(6):556-65. doi: 10.1056/NEJMra1507638.
8
[Digital necrosis after local anaesthesia with epinephrine].[肾上腺素局部麻醉后的数字坏死]
Ned Tijdschr Geneeskd. 2015;159:A9477.
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Safety of Epinephrine in Digital Nerve Blocks: A Literature Review.肾上腺素在指神经阻滞中的安全性：文献综述
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Prevalence, risk factors and associations of primary Raynaud's phenomenon: systematic review and meta-analysis of observational studies.原发性雷诺现象的患病率、危险因素及相关性：观察性研究的系统评价和荟萃分析
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