Ducor Leana, Dubi Guillaume, Christin Alexia, Rouiller Nathalie
Service de médecine interne et des soins intensifs, Groupement hospitalier de l'Ouest lémanique, Hôpital de Nyon, 1260 Nyon.
Médecin agréée en endocrinologie et diabétologie, Groupement hospitalier de l'Ouest lémanique, Hôpital de Nyon, 1260 Nyon.
Rev Med Suisse. 2022 Sep 7;18(794):1649-1655. doi: 10.53738/REVMED.2022.18.794.1649.
Acute adrenal insufficiency is a rare pathology which can be life threatening if not diagnosed and treated adequately. Clinical presentation is aspecific. Etiologies are classified as central or adrenal origins. Diagnosis of adrenal insufficiency is based on dosage of morning cortisol combined with a Synacthen test. When acute adrenal insufficiency is suspected, 100 mg of hydrocortisone should be administered as soon as possible, even before biological confirmation. This article, illustrated by a clinical case, will review the clinical presentation, diagnostic approach, and treatment of adrenal insufficiency.
急性肾上腺功能不全是一种罕见的病症，如果未得到充分诊断和治疗，可能会危及生命。临床表现缺乏特异性。病因分为中枢性或肾上腺源性。肾上腺功能不全的诊断基于清晨皮质醇测定并结合促肾上腺皮质激素（Synacthen）试验。当怀疑有急性肾上腺功能不全时，即使在生物学确诊之前，也应尽快给予100毫克氢化可的松。本文将通过一个临床病例进行阐述，回顾肾上腺功能不全的临床表现、诊断方法及治疗。
