Ouzounian T J, Thompson L, Grogan T J, Webber M M, Amstutz H C
Clin Orthop Relat Res. 1987 Aug(221):304-11.
The detection of musculoskeletal sepsis, especially following joint replacement, continues to be a challenging problem. Often, even with invasive diagnostic evaluation, the diagnosis of infection remains uncertain. This is a report on the first 55 Indium-111 white blood cell (WBC) images performed in 39 patients for the evaluation of musculoskeletal sepsis. There were 40 negative and 15 positive Indium-111 WBC images. These were correlated with operative culture and tissue pathology, aspiration culture, and clinical findings. Thirty-eight images were performed for the evaluation of possible total joint sepsis (8 positive and 30 negative images); 17 for the evaluation of nonarthroplasty-related musculoskeletal sepsis (7 positive and 10 negative images). Overall, there were 13 true-positive, 39 true-negative, two false-positive, and one false-negative images. Indium-111 WBC imaging is a sensitive and specific means of evaluating musculoskeletal sepsis, especially following total joint replacement.
肌肉骨骼系统败血症的检测，尤其是在关节置换术后，仍然是一个具有挑战性的问题。通常，即使进行了侵入性诊断评估，感染的诊断仍不确定。这是一份关于对39例患者进行的首批55例铟111白细胞（WBC）显像的报告，用于评估肌肉骨骼系统败血症。铟111白细胞显像有40例阴性和15例阳性。这些结果与手术培养、组织病理学、穿刺培养及临床发现相关。38例显像用于评估可能的全关节败血症（8例阳性和30例阴性显像）；17例用于评估与非关节置换相关的肌肉骨骼系统败血症（7例阳性和10例阴性显像）。总体而言，有13例真阳性、39例真阴性、2例假阳性和1例假阴性显像。铟111白细胞显像对于评估肌肉骨骼系统败血症，尤其是全关节置换术后的败血症，是一种敏感且特异的方法。
