Department of Health Promotion and Behavior (L.M.R.-H.), Institute of Gerontology, University of Georgia, Athens, GA; and Research & Development, Johnson & Johnson Vision Care Inc. (J.B., J.X.), Jacksonville, FL; and Vision Sciences Laboratory, Behavioral and Brain Sciences Program, University of Georgia (B.R.H.), Athens, GA.
Eye Contact Lens. 2022 Dec 1;48(12):516-520. doi: 10.1097/ICL.0000000000000935. Epub 2022 Sep 7.
Glare discomfort (GDC) is the slight pain (discomfort) that arises when exposed to light that exceeds one's adaptive state. Such light can also cause a temporary loss in visual function (photostress, PS). We tested the hypothesis that filtering with a high-energy visible (HEV) light-filtering contact lens can reduce GDC and speed PS recovery time.
Sixty-one subjects were randomized and fit with study lenses and 58 subjects completed as cohort (20-65 years of age). A double-masked, randomized, contralateral design was used (HEV filter on one eye; control lens on the other). Participants were given a 5-s exposure to a broadband white photostressor. Video images were analyzed, and palpebral fissure size during exposure was measured, as was PS recovery time to a 2-degree mid-wave target.
The HEV-filtering test lens was statistically superior ( P <0.0001) to the clear comparison contact lens with respect to the magnitude of squint (44.9% squint reduction) and photostress recovery time (24.3% faster recovery).
High-energy visible light-filtering contacts can reduce GDC and speed PS recovery. Filtering HEV light before it is incident upon the retina is a natural strategy (e.g., by the lens and macular pigment) for attenuating some of the deleterious effects of bright broadband light.
眩光不适（GDC）是指当暴露在超过适应状态的光线下时出现的轻微疼痛（不适）。这种光也会导致视觉功能暂时丧失（光应激，PS）。我们假设通过高能可见光（HEV）滤光隐形眼镜过滤可以减少 GDC 并加速 PS 恢复时间。
61 名受试者被随机分配并佩戴研究镜片，其中 58 名受试者完成了队列研究（20-65 岁）。采用双盲、随机、对侧设计（一只眼戴 HEV 滤光片；另一只眼戴对照镜片）。参与者接受了 5 秒的宽带白色光应激照射。分析视频图像，并测量暴露期间的睑裂大小，以及恢复到 2 度中波目标的 PS 恢复时间。
HEV 滤光测试镜片在斜视幅度（减少 44.9%）和光应激恢复时间（快 24.3%）方面明显优于透明对照隐形眼镜（P <0.0001）。
高能可见光滤光隐形眼镜可以减少 GDC 并加速 PS 恢复。在光进入视网膜之前过滤 HEV 光，是一种减轻强光宽带光的一些有害影响的自然策略（例如，通过晶状体和黄斑色素）。
