State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
Methods Mol Biol. 2022;2541:63-66. doi: 10.1007/978-1-0716-2545-3_10.
DNA-compatible C-H activations expand the chemical space of DNA-encoded library. Here we describe the ruthenium-promoted C-H activation between DNA-conjugated acrylamides and aromatic acid.
DNA 兼容的 C-H 活化扩展了 DNA 编码文库的化学空间。在这里,我们描述了 DNA 键合丙烯酰胺和芳族酸之间的钌促进的 C-H 活化。