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考虑进行食物过敏口服免疫疗法的患者的信息需求。

Information needs of patients considering oral immunotherapy for food allergy.

作者信息

Mack Douglas Paul, Greenhawt Matthew, Turner Paul J, Wasserman Richard L, Hanna Mariam A, Shaker Marcus, Hughes Sarah W, Del Río Pablo Rodríguez

机构信息

Halton Pediatric Allergy, McMaster University, Hamilton, Ontario, Canada.

Children's Hospital Colorado, University of Colorado School of Medicine, Aurora, Colorado, USA.

出版信息

Clin Exp Allergy. 2022 Dec;52(12):1391-1402. doi: 10.1111/cea.14225. Epub 2022 Sep 21.

Abstract

While the historic management of food allergy includes avoidance strategies and allergic reaction treatment, oral immunotherapy (OIT) approaches have become more commonly integrated into therapeutic approaches. International guidelines, phase 3 trials and real-world experience have supported the implementation of this procedure. However, OIT is an elective, rarely curative procedure with inherent risks that necessitates an increased degree of health literacy for the patients and families. Families assume the responsibility of amateur healthcare providers to ensure the daily safe administration of the allergenic food. As such, it is incumbent upon physicians to ensure that families are prepared for this role. A thorough educational and shared decision-making approach is necessary during the counselling and consent process to adequately inform the families. Educated discussion about the efficacy and patient-centred effectiveness, therapeutic alternatives and family goals is required to align physician and patient expectations. A frank discussion about the struggles, practical challenges, risks and contraindications can help to develop an understanding of the risk mitigation strategies employed to maintain safety. Physicians should develop a proactive approach to educate families about this, at times, burdensome procedure. This educational approach should encourage ongoing support starting prior to consent through the maintenance visits. By preparing families for their unique management role, physicians can help ensure the safe and successful integration of OIT into the therapeutic offering for the management of food allergies.

摘要

虽然食物过敏的传统管理方法包括回避策略和过敏反应治疗,但口服免疫疗法(OIT)已越来越普遍地纳入治疗方法中。国际指南、3期试验和实际经验都支持了这一程序的实施。然而,OIT是一种选择性的、很少能治愈的程序,存在固有风险,这就要求患者及其家庭提高健康素养。家庭承担起业余医疗服务提供者的责任,以确保每天安全地给予致敏食物。因此,医生有责任确保家庭为此做好准备。在咨询和同意过程中,需要采取全面的教育和共同决策方法,以便充分告知家庭相关信息。需要进行关于疗效、以患者为中心的有效性、治疗替代方案和家庭目标的教育性讨论,以使医生和患者的期望保持一致。坦诚地讨论困难、实际挑战、风险和禁忌证,有助于理解为维持安全而采用的风险缓解策略。医生应该采取积极主动的方法,向家庭介绍这种有时很繁琐的程序。这种教育方法应该鼓励从同意前开始一直到维持随访都给予持续支持。通过让家庭为其独特的管理角色做好准备,医生可以帮助确保OIT安全、成功地纳入食物过敏管理的治疗方案中。

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