Department of Otolaryngology, The Royal Children's Hospital Melbourne, 3052, Parkville, Victoria, Australia.
Department of Otolaryngology, The Royal Children's Hospital Melbourne, 3052, Parkville, Victoria, Australia.
Int J Pediatr Otorhinolaryngol. 2022 Nov;162:111294. doi: 10.1016/j.ijporl.2022.111294. Epub 2022 Sep 5.
Myxedema is a manifestation of severe hypothyroidism, and when affecting the larynx it constitutes a rare cause of upper airway obstruction. We present a case of laryngeal myxedema in a newborn causing subglottic stenosis. The atypical aspect of the stenosis along with a thyroid goiter and a positive screening for neonatal hypothyroidism allowed the diagnosis of laryngeal myxedema. Thyroid hormone replacement and non-invasive ventilation led to quick resolution while avoiding invasive approaches. Laryngeal myxedema is possibly underdiagnosed. Physician awareness is essential to avoid pitfalls in such children with reversible airway obstruction.
黏液水肿是严重甲状腺功能减退的一种表现,当影响喉部时,它构成了上呼吸道阻塞的罕见原因。我们报告了一例新生儿喉黏液水肿导致声门下狭窄的病例。狭窄的非典型表现,加上甲状腺肿和新生儿甲状腺功能减退症的阳性筛查,有助于诊断喉黏液水肿。甲状腺激素替代和无创通气导致快速缓解,同时避免了有创方法。喉黏液水肿可能被漏诊。医生的意识对于避免这些具有可逆转气道阻塞的儿童出现陷阱至关重要。