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喉黏液性水肿:甲状腺功能减退症一种罕见并发症的文献综述

Laryngeal myxoedema: a literature review of an uncommon complication of hypothyroidism.

作者信息

Iftikhar Mian Harris, Raziq Fazal I, Coll Patrick, Dar Aneeqa Yousaf

机构信息

Michigan State University, East Lansing, Michigan, USA.

Michigan State University College of Human Medicine, East Lansing, Michigan, USA

出版信息

BMJ Case Rep. 2021 Apr 1;14(4):e241313. doi: 10.1136/bcr-2020-241313.

Abstract

A 59-year-old woman presented to the emergency department with shortness of breath. She had significant oropharyngeal swelling obstructing her upper respiratory tract. A diagnosis of laryngeal myxoedema was made, which was attributed to severe hypothyroidism. She required invasive ventilation and subsequently a tracheostomy. She was treated with levothyroxine and hydrocortisone. She completely recovered with this therapy. In this review, we will discuss similar cases and different therapeutic options. This case also highlights the fact that establishing a diagnosis of laryngeal myxoedema, a condition that can potentially have lethal outcomes and can be challenging.

摘要

一名59岁女性因呼吸急促被送往急诊科。她有明显的口咽肿胀,阻塞了上呼吸道。诊断为喉黏液性水肿,病因是严重甲状腺功能减退。她需要有创通气,随后进行了气管切开术。给予左甲状腺素和氢化可的松治疗。经此治疗,她完全康复。在本综述中,我们将讨论类似病例及不同的治疗选择。该病例还凸显了这样一个事实,即喉黏液性水肿的诊断颇具挑战性,这种疾病可能会导致致命后果。

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本文引用的文献

1
Pulmonary consequences of hypothyroidism.甲状腺功能减退的肺部后果。
Ann Thorac Med. 2017 Jul-Sep;12(3):204-208. doi: 10.4103/atm.ATM_364_16.
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Med Clin North Am. 2012 Mar;96(2):385-403. doi: 10.1016/j.mcna.2012.01.015. Epub 2012 Feb 17.
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Identification of thyroid hormone receptors in the human larynx.人喉中甲状腺激素受体的鉴定。
Laryngoscope. 2003 Nov;113(11):1931-4. doi: 10.1097/00005537-200311000-00014.

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