BlaDimiR：一种用于准确诊断和随访膀胱癌的尿液微小RNA评分 - Suppr

BlaDimiR: A Urine-based miRNA Score for Accurate Bladder Cancer Diagnosis and Follow-up.

作者信息

Suarez-Cabrera Cristian, Estudillo Lidia, Ramón-Gil Erik, Martínez-Fernández Mónica, Peral Jorge, Rubio Carolina, Lodewijk Iris, Martín de Bernardo Álvaro, García-Escudero Ramón, Villacampa Felipe, Duarte José, de la Rosa Federico, Castellano Daniel, Guerrero-Ramos Félix, Real Francisco X, Malats Núria, Paramio Jesús M, Dueñas Marta

机构信息

Biomedical Research Institute, University Hospital 12 de Octubre, Madrid, Spain; Centro de Investigación Biomédica en Red de Cáncer, Madrid, Spain; Molecular Oncology Unit, Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas, Madrid, Spain.

Genetic and Molecular Epidemiology Group, Spanish National Cancer Research Centre CNIO, Madrid, Spain.

出版信息

Eur Urol. 2022 Dec;82(6):663-667. doi: 10.1016/j.eururo.2022.08.011. Epub 2022 Sep 6.

DOI:10.1016/j.eururo.2022.08.011

PMID:36085102

Abstract

摘要

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BlaDimiR: A Urine-based miRNA Score for Accurate Bladder Cancer Diagnosis and Follow-up.BlaDimiR：一种用于准确诊断和随访膀胱癌的尿液微小RNA评分

Eur Urol. 2022 Dec;82(6):663-667. doi: 10.1016/j.eururo.2022.08.011. Epub 2022 Sep 6.

MicroRNAs in tumor samples and urinary extracellular vesicles as a putative diagnostic tool for muscle-invasive bladder cancer.肿瘤样本和尿液细胞外囊泡中的 microRNAs 作为肌肉浸润性膀胱癌的一种潜在诊断工具。

J Cancer Res Clin Oncol. 2019 Nov;145(11):2725-2736. doi: 10.1007/s00432-019-03035-6. Epub 2019 Sep 24.

Expression profile of microRNAs (106b-3p, 130b-3, 145-3p, 199a-5p) in urine and serum samples from patients with the diagnosis of bladder cancer.膀胱癌患者尿液和血清样本中 microRNAs（106b-3p、130b-3、145-3p、199a-5p）的表达谱。

Pol Merkur Lekarski. 2021 Apr 18;49(290):103-107.

Urinary exosomal microRNA-96-5p and microRNA-183-5p expression as potential biomarkers of bladder cancer.尿外泌体 microRNA-96-5p 和 microRNA-183-5p 表达作为膀胱癌潜在生物标志物。

Mol Biol Rep. 2021 May;48(5):4361-4371. doi: 10.1007/s11033-021-06451-5. Epub 2021 Jun 4.

Aberrant expression of microRNAs in bladder cancer.膀胱癌中 microRNAs 的异常表达。

Nat Rev Urol. 2013 Jul;10(7):396-404. doi: 10.1038/nrurol.2013.113. Epub 2013 May 28.

Comparison of MicroRNA Content in Plasma and Urine Indicates the Existence of a Transrenal Passage of Selected MicroRNAs.血浆和尿液中微小RNA含量的比较表明特定微小RNA存在经肾通道。

Adv Exp Med Biol. 2016;924:97-100. doi: 10.1007/978-3-319-42044-8_18.

A urinary microRNA (miR) signature for diagnosis of bladder cancer.用于诊断膀胱癌的尿液微小RNA（miR）特征

Urol Oncol. 2018 Dec;36(12):531.e1-531.e8. doi: 10.1016/j.urolonc.2018.09.006. Epub 2018 Oct 12.

MicroRNAs as noninvasive biomarkers in bladder cancer detection: a diagnostic meta-analysis based on qRT-PCR data.微小RNA作为膀胱癌检测中的无创生物标志物：基于qRT-PCR数据的诊断性荟萃分析

Int J Biol Markers. 2016 Jul 30;31(3):e276-85. doi: 10.5301/jbm.5000199.

Genome-wide identification of urinary cell-free microRNAs for non-invasive detection of bladder cancer.利用全基因组鉴定尿细胞游离 microRNAs 进行膀胱癌的无创检测。

J Cell Mol Med. 2018 Mar;22(3):2033-2038. doi: 10.1111/jcmm.13487. Epub 2018 Jan 24.

Urinary miRNA profiles discriminate between obstruction-induced bladder dysfunction and healthy controls.尿 microRNA 谱可区分梗阻性膀胱功能障碍与健康对照。

Sci Rep. 2021 May 13;11(1):10204. doi: 10.1038/s41598-021-89535-3.

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Characterisation of Gene Expression in Canine Invasive Urothelial Carcinoma Using a NanoString-Based Urine Assay.使用基于NanoString的尿液检测法对犬浸润性尿路上皮癌中的基因表达进行表征

Vet Comp Oncol. 2025 Jun;23(2):205-215. doi: 10.1111/vco.13046. Epub 2025 Mar 19.

Unleashing the power of urine‑based biomarkers in diagnosis, prognosis and monitoring of bladder cancer (Review).释放基于尿液的生物标志物在膀胱癌诊断、预后和监测中的力量（综述）。

Int J Oncol. 2025 Mar;66(3). doi: 10.3892/ijo.2025.5724. Epub 2025 Feb 7.

Epigenetic Biomarkers as a New Diagnostic Tool in Bladder Cancer-From Early Detection to Prognosis.表观遗传生物标志物作为膀胱癌的新型诊断工具——从早期检测到预后

J Clin Med. 2024 Nov 26;13(23):7159. doi: 10.3390/jcm13237159.

Screening Model for Bladder Cancer Early Detection With Serum miRNAs Based on Machine Learning: A Mixed-Cohort Study Based on 16,189 Participants.基于机器学习的血清 miRNAs 膀胱癌早期检测筛查模型：一项基于 16189 名参与者的混合队列研究。

Cancer Med. 2024 Oct;13(20):e70338. doi: 10.1002/cam4.70338.

TRIM27 revealing by tumor educated platelet RNA-sequencing, as a potential biomarker for malignant ground-glass opacities diagnosis mediates glycolysis of non-small cell lung cancer cells partially through HOXM1.通过肿瘤驯化血小板RNA测序揭示的TRIM27，作为恶性磨玻璃影诊断的潜在生物标志物，部分通过HOXM1介导非小细胞肺癌细胞的糖酵解。

Transl Lung Cancer Res. 2024 Sep 30;13(9):2307-2325. doi: 10.21037/tlcr-24-157. Epub 2024 Sep 24.

Use of genomic markers to improve epidemiologic and clinical research in urology.利用基因组标志物提高泌尿科的流行病学和临床研究。

Curr Opin Urol. 2023 Nov 1;33(6):414-420. doi: 10.1097/MOU.0000000000001126. Epub 2023 Aug 29.

Urinary MicroRNAs as Biomarkers of Urological Cancers: A Systematic Review.尿 MicroRNAs 作为泌尿系统癌症的生物标志物：系统评价。

Int J Mol Sci. 2023 Jun 29;24(13):10846. doi: 10.3390/ijms241310846.

The relationship between microRNAs and bladder cancer: are microRNAs useful to predict bladder cancer in suspicious patients?microRNAs 与膀胱癌的关系：microRNAs 是否有助于预测疑似膀胱癌患者的膀胱癌？

Int Urol Nephrol. 2023 Oct;55(10):2483-2491. doi: 10.1007/s11255-023-03666-2. Epub 2023 Jun 20.

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BlaDimiR: A Urine-based miRNA Score for Accurate Bladder Cancer Diagnosis and Follow-up.

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