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Rev Colomb Psiquiatr (Engl Ed). 2022 Jul-Sep;51(3):245-255. doi: 10.1016/j.rcpeng.2020.11.008. Epub 2022 Sep 1.
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本文引用的文献

1
Survey of psychiatrists and psychiatry residents in Colombia about their preventive and therapeutic practices in delirium.对哥伦比亚精神科医生和精神科住院医师关于他们在谵妄方面的预防和治疗实践的调查。
Rev Colomb Psiquiatr (Engl Ed). 2020 May 28. doi: 10.1016/j.rcp.2020.02.003.
2
An overview of the safety, clinical application and antiviral research of the COVID-19 therapeutics.新型冠状病毒治疗药物的安全性、临床应用和抗病毒研究概述。
J Infect Public Health. 2020 Oct;13(10):1405-1414. doi: 10.1016/j.jiph.2020.07.004. Epub 2020 Jul 13.
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Dexamethasone in Hospitalized Patients with Covid-19.地塞米松在 COVID-19 住院患者中的应用。
N Engl J Med. 2021 Feb 25;384(8):693-704. doi: 10.1056/NEJMoa2021436. Epub 2020 Jul 17.
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Coronavirus 2019 Disease (COVID-19), Systemic Inflammation, and Cardiovascular Disease.2019冠状病毒病(COVID-19)、全身炎症与心血管疾病
J Am Heart Assoc. 2020 Aug 18;9(16):e017756. doi: 10.1161/JAHA.120.017756. Epub 2020 Jul 17.
5
Vascular risk factors, Framingham risk score, and COVID-19: community-based cohort study.血管危险因素、弗雷明汉风险评分与2019冠状病毒病:基于社区的队列研究
Cardiovasc Res. 2020 Aug 1;116(10):1664-1665. doi: 10.1093/cvr/cvaa178.
6
Why the elderly appear to be more severely affected by COVID-19: The potential role of immunosenescence and CMV.为什么老年人似乎更容易受到 COVID-19 的严重影响:免疫衰老和 CMV 的潜在作用。
Rev Med Virol. 2020 Sep;30(5):e2144. doi: 10.1002/rmv.2144. Epub 2020 Jul 15.
7
Therapeutic Plasma Exchange: A potential Management Strategy for Critically Ill COVID-19 Patients.治疗性血浆置换:危重症COVID-19患者的一种潜在管理策略。
J Intensive Care Med. 2020 Sep;35(9):827-835. doi: 10.1177/0885066620940259. Epub 2020 Jul 15.
8
Delirium as the first clinical presentation of the coronavirus disease 2019 in an older adult.谵妄作为一名老年人2019冠状病毒病的首发临床表现。
Psychogeriatrics. 2020 Sep;20(5):763-765. doi: 10.1111/psyg.12587. Epub 2020 Jul 14.
9
A Randomized Clinical Trial of the Efficacy and Safety of Interferon β-1a in Treatment of Severe COVID-19.一项干扰素 β-1a 治疗重症 COVID-19 的疗效和安全性的随机临床试验。
Antimicrob Agents Chemother. 2020 Aug 20;64(9). doi: 10.1128/AAC.01061-20.
10
Vaccines for COVID-19: The current state of play.COVID-19 疫苗:当前进展状况。
Paediatr Respir Rev. 2020 Sep;35:43-49. doi: 10.1016/j.prrv.2020.06.010. Epub 2020 Jun 18.

哥伦比亚精神病学协会联络精神病学委员会关于 COVID-19 大流行背景下谵妄的诊断和治疗的共识。

Consensus of the Liaison-Psychiatry Committee of the Colombian Psychiatric Association on the diagnosis and treatment of delirium in the context of the COVID-19 pandemic.

机构信息

Escuela de Ciencias de la Salud, Facultad de Medicina, Grupo de Investigación en Psiquiatría de Enlace (GIPE), Universidad Pontificia Bolivariana, Medellín, Colombia.

Hospital Universitario Fundación Santa Fe de Bogotá, Bogotá, Colombia; Facultad de Medicina, Departamento de Salud Mental, Grupo de Investigación Fundamental: Psiquiatría de Enlace Salud Poblacional, Uniandes, Bogotá, Colombia.

出版信息

Rev Colomb Psiquiatr (Engl Ed). 2022 Jul-Sep;51(3):245-255. doi: 10.1016/j.rcpeng.2020.11.008. Epub 2022 Sep 1.

DOI:10.1016/j.rcpeng.2020.11.008
PMID:36085127
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9433347/
Abstract

The pandemic caused by the new coronavirus named SARS-CoV-2 poses unprecedented challenges in the health care. Among them is the increase in cases of delirium. The severe SARS-CoV-2 disease, COVID-19, has common vulnerabilities with delirium and produces alterations in organs such as the lungs or the brain, among others, which have the potential to trigger the mental disorder. In fact, delirium may be the first manifestation of the infection, before fever, general malaise, cough or respiratory disturbances. It is widely supported that delirium increases the morbidity and mortality in those who suffer from it during hospitalization, so it should be actively sought to carry out the relevant interventions. In the absence of evidence on the approach to delirium in the context of COVID-19, this consensus was developed on three fundamental aspects: diagnosis, non-pharmacological treatment and pharmacological treatment, in patients admitted to the general hospital. The document contains recommendations on the systematic use of diagnostic tools, when to hospitalize the patient with delirium, the application of non-pharmacological actions within the restrictions imposed by COVID-19, and the use of antipsychotics, taking into account the most relevant side effects and pharmacological interactions.

摘要

由新型冠状病毒 SARS-CoV-2 引起的大流行给医疗保健带来了前所未有的挑战。其中包括谵妄病例的增加。严重的 SARS-CoV-2 疾病 COVID-19 与谵妄有共同的脆弱性,并会导致肺部或大脑等器官的改变,这些都有可能引发精神障碍。事实上,谵妄可能是感染的首发症状,早于发热、全身不适、咳嗽或呼吸紊乱等症状。广泛认为,谵妄会增加住院患者的发病率和死亡率,因此应积极寻求相关干预措施。鉴于 COVID-19 背景下谵妄治疗方法缺乏证据,本共识主要针对综合医院收治的患者,就诊断、非药物治疗和药物治疗三个基本方面达成了一致意见。该文件就诊断工具的系统使用、何时将谵妄患者收入院、在 COVID-19 限制范围内实施非药物治疗、以及考虑到最相关的副作用和药物相互作用时使用抗精神病药物等方面提出了建议。