药物治疗与认知行为疗法在治疗酒精使用障碍中的相互作用及附加价值：一项系统综述。
The Added Value of Pharmacotherapy to Cognitive Behavior Therapy And Vice Versa in the Treatment of Alcohol Use Disorders: A Systematic Review.
机构信息
Amsterdam UMC, University of Amsterdam, Department of Psychiatry, Amsterdam Neuroscience, Research Program Compulsivity, Impulsivity & Attention, P.O. Box 22660, 1100 DD, Amsterdam, The Netherlands.
Parnassia Addiction Research Centre (PARC), Parnassia Psychiatric Institute, Zoutkeetsingel 40, 2512 HN, The Hague, The Netherlands.
出版信息
Alcohol Alcohol. 2022 Nov 11;57(6):768-775. doi: 10.1093/alcalc/agac043.
AIM
To explore whether combined interventions i.e. psychotherapeutic plus psychosocial interventions are more effective than monotherapies in the treatment of alcohol use disorders.
METHODS
Systematic review of the results of randomized controlled trials that compared combined therapies with monotherapies (either pharmacotherapy or psychotherapy).
RESULTS
The search resulted in 28 eligible studies. Data from these RCTs showed that 10 out of 19 RCTs (53%) demonstrated an added value of combined therapy (psychotherapy + pharmacotherapy) compared to psychotherapy only, whereas only three out of nine RCTs (33%) comparing combined therapy with pharmacotherapy showed a possible added value for combined therapy.
CONCLUSIONS
Pharmacotherapy is effective to treat AUD with or without psychotherapy and that psychotherapy can best be offered in combination with pharmacotherapy.
目的
探讨心理治疗联合心理社会干预是否比单一疗法更能有效治疗酒精使用障碍。
方法
对随机对照试验的结果进行系统回顾，比较联合疗法（药物治疗或心理治疗）与单一疗法的疗效。
结果
搜索结果得到 28 项符合条件的研究。这些 RCT 的数据表明，19 项 RCT 中有 10 项（53%）显示联合治疗（心理治疗+药物治疗）比单纯心理治疗更有价值，而 9 项 RCT 中有 3 项（33%）比较联合治疗与药物治疗，显示联合治疗可能有附加价值。
结论
药物治疗对 AUD 有效，无论是否联合心理治疗，心理治疗最好与药物治疗联合应用。
Zotero 插件