Annu Int Conf IEEE Eng Med Biol Soc. 2022 Jul;2022:865-868. doi: 10.1109/EMBC48229.2022.9871148.
One in every eight women will get breast cancer during their lifetime. Therefore, the early diagnosis of the lesions is fundamental to improve the chances of recovery. To find breast cancers, breast screening using techniques such as mammography and ultrasound (US) imaging scans are often used. When a lesion is found, a breast biopsy is performed to extract a tissue sample for analysis. The breast biopsy is usually assisted by an US to help find the lesion and guide the needle to its location. However, the identification of the needle tip in US image is challenging, possibly resulting in puncture failures. In this paper, we intend to study the potential of a sensorized needle guide system that provides information about the needle angle and displacement in respect to the US probe. Laboratory tests were initially conducted to evaluate the accuracy of each sensor in controlled conditions. After, a practical experiment with the US probe, working as a proof of concept, was performed. The angle sensor showed a root mean square error (RMSE) of 0.48 degrees and the displacement sensor showed a RMSE of 0.26mm after being calibrated. For the US probe tests, the displacement sensor shows high errors in the range of 1.19mm to 2.05mm due to mechanical reasons. Overall, the proposed system showed its potential to be used to accurately estimate needle tip localization throughout breast biopsies guided by US, corroborating its potential clinical application. Clinical relevance - Potential for clinical application where precise needle localization in ultrasound image is required.
每 8 个女性中就有 1 个会在其一生中患上乳腺癌。因此，早期诊断病变对于提高康复机会至关重要。为了发现乳腺癌，通常使用乳腺筛查技术，如乳房 X 线摄影术和超声（US）成像扫描。当发现病变时，进行乳腺活检以提取组织样本进行分析。乳腺活检通常由 US 辅助，以帮助找到病变并引导针到达其位置。然而，US 图像中针尖的识别具有挑战性，可能导致穿刺失败。在本文中，我们旨在研究一种传感器化的针引导系统的潜力，该系统提供有关相对于 US 探头的针角度和位移的信息。最初在受控条件下进行了实验室测试，以评估每个传感器的准确性。然后，使用 US 探头进行了实际实验，作为概念验证。角度传感器在经过校准后显示出 0.48 度的均方根误差（RMSE），而位移传感器显示出 0.26mm 的 RMSE。对于 US 探头测试，由于机械原因，位移传感器在 1.19mm 至 2.05mm 的范围内显示出较高的误差。总体而言，所提出的系统显示出其在 US 引导的乳腺活检中准确估计针尖定位的潜力，证实了其在临床应用中的潜力。临床相关性-在需要精确的超声图像中定位针的情况下具有临床应用的潜力。
