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脊髓经皮电刺激可实现运动完全性 SCI 患者的膝关节主动伸展。

Spinal Cord Transcutaneous Stimulation Enables Volitional Knee Extension in Motor-complete SCI.

出版信息

Annu Int Conf IEEE Eng Med Biol Soc. 2022 Jul;2022:2373-2376. doi: 10.1109/EMBC48229.2022.9871966.

DOI:10.1109/EMBC48229.2022.9871966
PMID:36085833
Abstract

Non-invasive spinal cord transcutaneous stimulation (scTS) is often applied to one or multiple spinal segments and may improve motor control after spinal cord injury (SCI). The purpose of this pilot study was to apply tonic scTS to an individual with motor-complete spinal cord injury (SCI) in order to initiate and maintain volitional control during a specific lower-extremity motor task. The participant's legs were placed in a gravity-neutral position, and he was asked to extend his knee, with and without the presence of tonic scTS. Our results show intentional voluntary control of knee extension with scTS (with no assistance). Our preliminary findings highlight how scTS neuromodulation of the spinal circuitry has the potential to restore motor function for people with motor-complete SCI. Clinical Relevance- This investigation is critical to better understand the neuromodulatory effects of tonic scTS for augmentation of voluntary-induced muscle activations in individuals with motor-complete SCI.

摘要

经皮脊髓无创刺激(scTS)通常应用于一个或多个脊髓节段,可改善脊髓损伤(SCI)后的运动控制。本初步研究的目的是对运动完全性 SCI 患者应用强直 scTS,以便在特定的下肢运动任务中启动和维持随意控制。将患者的腿部置于零重力位置,并要求他伸展膝盖,同时施加和不施加强直 scTS。我们的结果表明,scTS 可(无需辅助)实现膝关节伸展的有意随意控制。我们的初步发现强调了脊髓电路强直 scTS 神经调节具有恢复运动完全性 SCI 患者运动功能的潜力。临床相关性-本研究对于更好地理解强直 scTS 的神经调节作用以增强运动完全性 SCI 患者的随意诱导肌肉活动至关重要。

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引用本文的文献

1
Transcutaneous spinal stimulation in people with and without spinal cord injury: Effect of electrode placement and trains of stimulation on threshold intensity.经皮脊髓刺激在脊髓损伤患者和非脊髓损伤患者中的应用:电极放置和刺激模式对阈值强度的影响。
Physiol Rep. 2023 Jun;11(11):e15692. doi: 10.14814/phy2.15692.