Brihmat N, Bayram M B, Ravi M, Bheemreddy A, Anjaria M, Momeni K, Saleh S, Forrest G F
Annu Int Conf IEEE Eng Med Biol Soc. 2023 Jul;2023:1-4. doi: 10.1109/EMBC40787.2023.10340957.
Spinal cord transcutaneous stimulation (scTS) has shown its potential for boosting motor, sensory, and autonomic function recovery after a spinal cord injury. Despite the demonstrated benefits, little is known about the exact neuromodulatory mechanisms triggered by scTS and the cortex involvement in the beneficial effects observed. Here, we examine the effects of scTS-based motor training and motor training alone on sensorimotor cortical functional connectivity and corticospinal excitability in able-bodied and SCI participants.Clinical Relevance- The results show preliminary evidence of differential cortical involvement and modulation by scTS-based motor training in uninjured and spinal-cord injured individuals. A better understanding of scTS mechanisms of action could help optimize the intervention design and potentiate its benefits.
脊髓经皮刺激（scTS）已显示出其在促进脊髓损伤后运动、感觉和自主神经功能恢复方面的潜力。尽管已证明其益处，但对于scTS触发的确切神经调节机制以及皮层在观察到的有益效果中的参与情况知之甚少。在这里，我们研究了基于scTS的运动训练和单独的运动训练对健全人和脊髓损伤参与者感觉运动皮层功能连接和皮质脊髓兴奋性的影响。临床意义——结果显示了初步证据，表明在未受伤和脊髓损伤个体中，基于scTS的运动训练对皮层的参与和调节存在差异。更好地理解scTS的作用机制有助于优化干预设计并增强其益处。
