文献检索文档翻译深度研究
Suppr Zotero 插件Zotero 插件
邀请有礼套餐&价格历史记录

新学期,新优惠

限时优惠:9月1日-9月22日

30天高级会员仅需29元

1天体验卡首发特惠仅需5.99元

了解详情
不再提醒
插件&应用
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
高级版
套餐订阅购买积分包
AI 工具
文献检索文档翻译深度研究
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2025

三叉神经千赫兹电刺激对运动学习的影响。

Effects of Kilohertz Electrical Stimulation of the Trigeminal Nerve on Motor Learning.

出版信息

Annu Int Conf IEEE Eng Med Biol Soc. 2022 Jul;2022:5103-5106. doi: 10.1109/EMBC48229.2022.9871095.


DOI:10.1109/EMBC48229.2022.9871095
PMID:36085879
Abstract

Neurological disorders such as stroke remain leading causes of disability worldwide. A current thrust in the neurorehabilitation of such disorders involves exogenous neuromodulation of cranial nerves in order to enhance neuro-plasticity and maximize recovery of function. Here we present preliminary results on the effects of kilohertz range electrical stimulation of the trigeminal nerve (TNS) on motor learning, using an upper extremity visuomotor adaptation paradigm. Twenty-five (25) healthy adult subjects were randomly assigned to 2 groups: 3kHz stimulation ( n=13) and sham ( n=12). Participants performed a visuomotor rotation task that involved center-out reaching movements to eight vertically arranged targets. Four blocks of trials were performed: two baseline blocks with veridical visual feedback, one adaptation block involving a 30° CCW rotation of hand visual feedback, and one washout block with no rotation. TNS was applied for 20 minutes before the 2nd baseline block using two electrodes targeting the ophthalmic branches of the trigeminal nerve. Early in the rotation block, learning rates were similar between the 3kHz and sham groups but gradually diverged, with the 3kHz group demonstrating slightly faster rates than sham later in the rotation block. The results provide new information on the potential use of TNS in neurorehabilitation.

摘要

神经紊乱疾病,如中风,仍然是全球范围内导致残疾的主要原因。目前,此类疾病的神经康复的一个重点是对外源性颅神经进行神经调节,以增强神经可塑性并最大限度地恢复功能。在这里,我们介绍了使用上肢视觉运动适应范式,对三叉神经(TNS)进行千赫兹范围电刺激对运动学习影响的初步结果。25 名健康成年受试者被随机分为 2 组:3kHz 刺激组(n=13)和假刺激组(n=12)。参与者进行了一项视觉运动旋转任务,包括向 8 个垂直排列的目标进行中心外伸运动。进行了 4 个试验块:2 个具有真实视觉反馈的基线块,1 个涉及手视觉反馈逆时针旋转 30°的适应块,1 个没有旋转的洗脱块。在第二个基线块之前,使用两个针对三叉神经眼支的电极进行 20 分钟的 TNS 治疗。在旋转块的早期,3kHz 组和假刺激组的学习率相似,但逐渐出现分歧,3kHz 组在旋转块的后期显示出比假刺激组稍快的学习率。这些结果为 TNS 在神经康复中的潜在应用提供了新的信息。

相似文献

[1]
Effects of Kilohertz Electrical Stimulation of the Trigeminal Nerve on Motor Learning.

Annu Int Conf IEEE Eng Med Biol Soc. 2022-7

[2]
No effects of cerebellar transcranial direct current stimulation on force field and visuomotor reach adaptation in young and healthy subjects.

J Neurophysiol. 2019-4-3

[3]
Stimulating the cerebellum affects visuomotor adaptation but not intermanual transfer of learning.

Cerebellum. 2013-12

[4]
Eye-Hand Coordination during Visuomotor Adaptation with Different Rotation Angles: Effects of Terminal Visual Feedback.

PLoS One. 2016-11-3

[5]
Goalkeepers' plasticity during learning of a whole-body visuomotor rotation in a stable or variable environment.

Eur J Sport Sci. 2023-11

[6]
Multiple motor learning strategies in visuomotor rotation.

PLoS One. 2010-2-24

[7]
Task-specific internal models for kinematic transformations.

J Neurophysiol. 2003-8

[8]
Target size matters: target errors contribute to the generalization of implicit visuomotor learning.

J Neurophysiol. 2016-8-1

[9]
Visuomotor adaptation and generalization with repeated and varied training.

Exp Brain Res. 2013-2-28

[10]
Online and post-trial feedback differentially affect implicit adaptation to a visuomotor rotation.

Exp Brain Res. 2014-9

引用本文的文献

[1]
Effects of online and offline trigeminal nerve stimulation on visuomotor learning.

Front Hum Neurosci. 2024-10-17

[2]
Effect of touch on proprioception: non-invasive trigeminal nerve stimulation suggests general arousal rather than tactile-proprioceptive integration.

Front Hum Neurosci. 2024-10-14

[3]
Trigeminal nerve stimulation: a current state-of-the-art review.

Bioelectron Med. 2023-12-13

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

推荐工具

医学文档翻译智能文献检索