Annu Int Conf IEEE Eng Med Biol Soc. 2022 Jul;2022:4022-4025. doi: 10.1109/EMBC48229.2022.9871484.
Jugular venous pulse (JVP) helps in the early detection of central venous pressure abnormalities and various cardiovascular diseases. Studies have been reported indicating that contour features of the JVP waveform provide crucial information regarding cardiac function. Although current ultrasound systems reliably provide the diameter measurements, they are limited by low frame rates resulting in poor resolution JVP cycles that are inadequate to yield distinguishable critical points. In this work, we propose an image-free high frame rate system for the assessment of JVP signals. The proposed A-mode ultrasound system acquires high fidelity JVP pulses with a temporal resolution of 4 ms and amplitude resolution of 10 µm. The functionality verification of the proposed system was performed by comparing it against a clinical-grade B-mode imaging system. A study was conducted on a cohort of 25 subjects in the 20-30 age group. While the system provided diameter measurements comparable to that of the imaging ones (r > 0.98, p < 0.05), it also yielded high-resolution JVP exhibiting the presence of all fiduciary points. This was a leveraging feature as opposed to the imaging system that possessed limited temporal and amplitude resolution. Clinical Relevance- The proposed system is a potential ultrasound means for measuring the diameter values from JV at the same time yielding the JVP critical points necessary for clinical analysis.
颈静脉脉冲（JVP）有助于早期发现中心静脉压异常和各种心血管疾病。有研究表明，JVP 波形的轮廓特征提供了有关心脏功能的关键信息。尽管目前的超声系统可靠地提供了直径测量值，但它们受到低帧率的限制，导致 JVP 周期的分辨率较差，无法提供可区分的关键点。在这项工作中，我们提出了一种用于评估 JVP 信号的无图像高帧率系统。所提出的 A 型超声系统以 4ms 的时间分辨率和 10μm 的幅度分辨率获取高保真 JVP 脉冲。通过将其与临床级 B 型成像系统进行比较，对所提出系统的功能验证进行了测试。对 25 名 20-30 岁年龄组的受试者进行了一项研究。虽然该系统提供的直径测量值与成像系统相当（r>0.98，p<0.05），但它还提供了高分辨率的 JVP，显示出所有关键参考点的存在。这是一个有别于成像系统的优势，因为后者的时间分辨率和幅度分辨率有限。临床相关性-所提出的系统是一种潜在的超声手段，可用于测量 JV 的直径值，同时产生用于临床分析的 JVP 关键参考点。
