High Frame-Rate A-Mode Ultrasound System for Jugular Venous Pulse Tracking: A Feasibility Study.

Jugular venous pulse (JVP) helps in the early detection of central venous pressure abnormalities and various cardiovascular diseases. Studies have been reported indicating that contour features of the JVP waveform provide crucial information regarding cardiac function. Although current ultrasound systems reliably provide the diameter measurements, they are limited by low frame rates resulting in poor resolution JVP cycles that are inadequate to yield distinguishable critical points. In this work, we propose an image-free high frame rate system for the assessment of JVP signals. The proposed A-mode ultrasound system acquires high fidelity JVP pulses with a temporal resolution of 4 ms and amplitude resolution of 10 µm. The functionality verification of the proposed system was performed by comparing it against a clinical-grade B-mode imaging system. A study was conducted on a cohort of 25 subjects in the 20-30 age group. While the system provided diameter measurements comparable to that of the imaging ones (r > 0.98, p < 0.05), it also yielded high-resolution JVP exhibiting the presence of all fiduciary points. This was a leveraging feature as opposed to the imaging system that possessed limited temporal and amplitude resolution. Clinical Relevance- The proposed system is a potential ultrasound means for measuring the diameter values from JV at the same time yielding the JVP critical points necessary for clinical analysis.