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协调稳定的不对称性与功能恢复:从适应性系统角度看功能可塑性

Reconciling stable asymmetry with recovery of function: an adaptive systems perspective on functional plasticity.

作者信息

Bullock D, Liederman J, Todorović D

出版信息

Child Dev. 1987 Jun;58(3):689-97.

PMID:3608644
Abstract

This article examines alternative ways of resolving an apparent paradox that has emerged from neuropsychological studies of language development: How can the developmentally stable functional asymmetry ("hemispheric specialization") observed in neurologically intact children be reconciled with the dramatic recovery of function often displayed following unilateral brain damage? The alternative resolutions we consider differ most critically in the roles they assign to lesion-induced neural reorganizations versus lesion-related release of preexisting functional potentials. Though arguments are given in favor of the latter as the primary factor in functional recovery, the primary goal of the article is to clarify the conceptual issues raised by recent empirical research.

摘要

本文探讨了解决一个明显悖论的不同方法,该悖论源于对语言发展的神经心理学研究:在神经功能正常的儿童中观察到的发育稳定的功能不对称(“半球特化”),如何与单侧脑损伤后经常出现的功能显著恢复相协调?我们考虑的不同解决方案在它们赋予损伤诱导的神经重组与损伤相关的预先存在的功能潜能释放的作用方面存在最关键的差异。尽管有人支持将后者作为功能恢复的主要因素,但本文的主要目标是阐明近期实证研究提出的概念性问题。

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