碘 125 籽植入联合化疗治疗合并原发性结肠癌的转移性胰腺腺癌：一例报告。
Iodine-125 seed implantation combined chemotherapy for metastatic pancreatic adenocarcinoma with primary colon cancer: A case report.
机构信息
Department of Hepatobiliary Surgery, Hunan Provincial People's Hospital/The First Affiliated Hospital of Hunan Normal University, Changsha, China.
Central Laboratory of The First Affiliated Hospital of Hunan Normal University, Changsha, China.
出版信息
Medicine (Baltimore). 2022 Sep 9;101(36):e30349. doi: 10.1097/MD.0000000000030349.
RATIONALE
Colon cancer has a distinct migration aptitude. However, pancreatic metastasis is rare and treatment of inoperable pancreatic cancers is seldom seen.
PATIENT CONCERNS
A 47-year-old woman presented 2-month history of abdominal pain and abdominal distention, with anal cessation of exhaust and defecation for 4 days. A colon cancer radical resection was performed when she diagnosed with colon cancer. After 26 months, the patient complained shoulder and back pain. Multiple intraperitoneal metastases and nonisolated pancreatic metastasis of colon cancer were diagnosed.
DIAGNOSIS
Metastatic pancreatic adenocarcinoma (MPA) with primary colon cancer.
INTERVENTION
Iodine-125 seed implantation combined chemotherapy.
OUTCOMES
She remains free of cancer metastasis and recurrence, and has a good quality of life during the period.
LESSONS SUBSECTIONS
Iodine-125 seed implantation is an effective and safe strategy for unresectable metastatic pancreatic cancer. Iodine-125 seed implantation combined with chemotherapy improve survival for advanced pancreatic metastasis of colon cancer.
背景
结肠癌具有明显的迁移能力。然而，胰腺转移较为罕见，且不可手术的胰腺癌治疗少见。
病例介绍
一名 47 岁女性，因腹痛、腹胀 2 个月，肛门停止排气排便 4 天就诊。诊断为结肠癌后行结肠癌根治术。26 个月后，患者出现肩背部疼痛。诊断为结肠癌多发腹腔内转移、孤立性胰腺转移。
诊断
原发性结肠癌伴转移性胰腺腺癌（MPA）。
干预措施
碘 125 粒子植入联合化疗。
结果
患者无癌症转移和复发，生活质量良好。
结论
碘 125 粒子植入是治疗不可切除转移性胰腺癌的有效且安全的策略。碘 125 粒子植入联合化疗可提高结肠癌晚期胰腺转移患者的生存率。
Zotero 插件