Mourya Ankur, Aggarwal Lalit Mohan, Choudhary Sunil, Shahi Uday Pratap, Sharma Neeraj, Prakash Rajiv, Mishra Ritusha
Department of Radiotherapy and Radiation Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
Department of Radiotherapy and Radiation Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
Brachytherapy. 2022 Nov-Dec;21(6):754-763. doi: 10.1016/j.brachy.2022.07.007. Epub 2022 Sep 7.
To design the different Polytetrafluoroethylene (PTFE) based flexible implant tubes using an in-house developed device and to evaluate them for High dose rate (HDR) interstitial brachytherapy using computer tomography images.
PTFE hollow tube having a 2 mm (6 French) outer diameter (OD) and 1.4 mm inner diameter (ID) was used to design in-house single and/or double leader flexible catheters for interstitial brachytherapy implant. An in-house Plastic Wire Drawing Plate (PWDP) machine was developed. Customization of PTFE hollow flexible implant tube (FIT) was done through PWDP. Different percentages of BaSO (5%, 10%, & 15%) were added to Nylon 6 to make radiopaque button. Various quality assurance tests were performed with the PTFE tubes implanted in the brinjal (phantom) before using them on the patients. That is, coupling of brachytherapy machine transfer tube with flexible PTFE Tubes, CT scan artifacts, tube kinks, breast template, and free-hand compatibility.
With the help of the PWDP machine, plastic wires of different lengths were made for single leader and double leader tubes. The different plastic leader ends of 1 cm to 50 cm lengths having 1 mm diameter were created. The radiopaque button of Nylon 6 in circular shape having 1 cm diameter and 0.5 cm thick was created. Developed radiopaque buttons were visible on CT scan images as well as on radiograph images.
PTFE tubes of the desired length can be made depending upon the size of the brachytherapy implant and are inexpensive than commercially available flexible implant tubes.
使用自行研发的设备设计不同的聚四氟乙烯（PTFE）基柔性植入管，并利用计算机断层扫描图像对其进行高剂量率（HDR）组织间近距离放射治疗评估。
使用外径为2毫米（6法式）、内径为1.4毫米的PTFE中空管来设计用于组织间近距离放射治疗植入的自制单导和/或双导柔性导管。开发了一台自制的塑料拉丝板（PWDP）机器。通过PWDP对PTFE中空柔性植入管（FIT）进行定制。将不同百分比（5%、10%和15%）的硫酸钡添加到尼龙6中制成不透射线纽扣。在将PTFE管用于患者之前，先将其植入茄子（体模）中进行各种质量保证测试。即近距离放射治疗机传输管与柔性PTFE管的耦合、CT扫描伪影、管扭结、乳房模板和徒手兼容性。
借助PWDP机器，制作了不同长度的用于单导和双导管的塑料线。制作了长度为1厘米至50厘米、直径为1毫米的不同塑料导头端。制作了直径为1厘米、厚度为0.5厘米的圆形尼龙6不透射线纽扣。在CT扫描图像以及射线照片图像上都能看到制作的不透射线纽扣。
可以根据近距离放射治疗植入物的尺寸制作所需长度的PTFE管，且比市售的柔性植入管便宜。
