Dagher F J, Alongi S V, Smith A
Angiology. 1978 Sep;29(9):641-53. doi: 10.1177/000331977802900901.
--Bacteriologic studies of 30 chronic leg ulcers were studied in 18 adult patients before and after treatment with a local cleansing agent, Debrisan.--Results show that all ulcers, whether clinically inflamed or not, are secondarily infected.--The majority of ulcers grew more than 1 type of organism, up to 6 different types in 1 single ulcer.--The use of Debrisan reduces the types of organisms and colony counts in ulcers, allowing healthy granulation and epithelialization to proceed normally.--Control of infection reduces surrounding local edema and erythema.--By reducing types of organisms and colony counts in chronic leg ulcers successful skin grafting was readily achieved.
——对18名成年患者的30处慢性腿部溃疡在使用局部清洁剂Debrisan治疗前后进行了细菌学研究。
——结果显示,所有溃疡,无论临床上是否有炎症,均继发感染。
——大多数溃疡培养出不止1种微生物,单个溃疡中最多有6种不同类型。
——使用Debrisan可减少溃疡中的微生物种类和菌落计数,使健康的肉芽组织形成和上皮形成正常进行。
——控制感染可减轻周围局部水肿和红斑。
——通过减少慢性腿部溃疡中的微生物种类和菌落计数,很容易成功进行皮肤移植。