Department of Chemistry, College of Science, Hebei Agricultural University, Baoding 071001 Hebei, PR. China.
College of Public Health, Hebei University, Baoding 071002 Hebei, PR. China.
J Chromatogr A. 2022 Oct 11;1681:463474. doi: 10.1016/j.chroma.2022.463474. Epub 2022 Sep 5.
Owing to various health threats associated with phthalic acid esters (PAEs), this category of endocrine-disrupting compounds has attracted more and more public scrutiny. However, the efficient preconcentration of PAEs from complex food-contacted plastics still remains challenging. Herein, three covalent triazine-based frameworks (CTFs) were constructed by facile Friedel-Crafts reactions of cyanuric chloride (CC), with triptycene (TPC), fluorene (FL) and 1,3,5-triphenylbenzene (TPB), respectively. Three CTFs were then employed as solid-phase microextraction (SPME) coatings for the extraction of PAEs. Benefiting from the large surface area and high pore volume, the newly-synthesized CC-TPC based SPME method exhibited large enrichment factors (978-2210), low limits of detection (0.027-0.10 ng g ), satisfactory linear ranges (0.09-20 ng g ), acceptable repeatabilities (4.3-9.6%) and high relative recoveries (92.0-104.6%).
由于邻苯二甲酸酯（PAEs）与各种健康威胁有关，这类内分泌干扰化合物引起了越来越多的公众关注。然而，从复杂的食品接触塑料中高效浓缩 PAEs 仍然具有挑战性。在此，通过氰尿酰氯（CC）与三亚苯（TPC）、芴（FL）和 1,3,5-三苯基苯（TPB）的简单傅克反应，构建了三种三嗪基骨架（CTFs）。然后，将三种 CTF 用作固相微萃取（SPME）涂层，以萃取 PAEs。由于具有较大的比表面积和较高的孔体积，新合成的 CC-TPC 基 SPME 方法表现出较大的富集因子（978-2210）、较低的检出限（0.027-0.10ng g-1）、令人满意的线性范围（0.09-20ng g-1）、可接受的重现性（4.3-9.6%）和较高的相对回收率（92.0-104.6%）。
