Department of Oral and Maxillofacial Surgery, Shanghai Stomatological Hospital, Fudan University.
Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, Fudan University.
J Oral Sci. 2022 Oct 1;64(4):294-299. doi: 10.2334/josnusd.22-0187. Epub 2022 Sep 12.
This study aimed to investigate the efficacy of piezosurgery (PI) in promoting immediate clotting after flapless extraction in patients undergoing dual antiplatelet therapy (DAPT).
In this randomized controlled trial, 80 DAPT patients were equally divided into the PI and turbine handpiece (TH) groups. Accordingly, flapless extraction of a single tooth using PI or TH was performed on each patient, and the immediate clotting status was evaluated. The results of the preoperative hematological examinations, surgery-related variables and postoperative complications were recorded for analysis.
Both groups presented with low platelet aggregation and similar coagulation functions. The PI group exhibited a higher proportion of patients with normal intra-alveolar clotting (≤30 min) (70% vs. 40%, P = 0.007) and fewer intraoperative complications (25% vs. 47.5%, P = 0.036) than that in the TH group. Logistic regression analysis indicated that the applied instrument was an independent risk factor for prolonged immediate bleeding (odds ratio = 3.10, 95% confidence interval: 1.20-8.00, P = 0.019). Intergroup differences were insignificant in terms of the other surgery-related variables and postoperative complications, except for the longer surgical duration in the PI group.
The application of PI may contribute to better immediate clotting in DAPT patients after flapless extraction compared with the use of TH.
本研究旨在探讨在接受双联抗血小板治疗(DAPT)的患者中,使用超声骨刀(PI)促进无瓣拔牙后即刻凝血的效果。
在这项随机对照试验中,80 名 DAPT 患者被平均分为 PI 组和涡轮手机(TH)组。相应地,每位患者均采用 PI 或 TH 进行无瓣拔牙,评估即刻凝血状态。记录术前血液学检查、手术相关变量和术后并发症的结果进行分析。
两组患者血小板聚集率均较低,凝血功能相似。PI 组正常牙槽内凝血(≤30 分钟)的患者比例(70%比 40%,P = 0.007)更高,术中并发症(25%比 47.5%,P = 0.036)更少。Logistic 回归分析表明,应用的仪器是即刻出血时间延长的独立危险因素(比值比=3.10,95%置信区间:1.20-8.00,P = 0.019)。两组间其他手术相关变量和术后并发症差异无统计学意义,除 PI 组手术时间较长外。
与使用 TH 相比,在 DAPT 患者无瓣拔牙后,PI 的应用可能有助于更好的即刻凝血。