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老年2型糖尿病患者胰岛素使用经历:一项主题综合分析

The experiences of insulin use among older people with Type 2 diabetes mellitus: A thematic synthesis.

作者信息

Langerman Chaya, Forbes Angus, Robert Glenn

机构信息

Florence Nightingale Faculty of Nursing, Midwifery and Palliative Care, King's College London, James Clerk Maxwell Building, 57 Waterloo Road, London SE1 8WA, United Kingdom.

Florence Nightingale Faculty of Nursing, Midwifery and Palliative Care, King's College London, James Clerk Maxwell Building, 57 Waterloo Road, London SE1 8WA, United Kingdom.

出版信息

Prim Care Diabetes. 2022 Oct;16(5):614-626. doi: 10.1016/j.pcd.2022.08.008. Epub 2022 Sep 8.

Abstract

BACKGROUND

Type 2 diabetes mellitus is common in older people. Managing diabetes in older people can be challenging due to comorbidities and age-related disabilities, particularly in the context of insulin therapy. The purpose of this review is to explore older people's experiences of insulin use and to consider how these experiences might inform healthcare delivery.

REVIEW METHODS

A systematic review with thematic synthesis was conducted and reported in accordance with the PRISMA and ENTREQ statements. MEDLINE, Embase, PsycInfo, CINAHL and Web of Science were searched from 1985 to September 2019 with subsequent updates in December 2019 and June 2022. Included studies were quality appraised, findings tabulated, and results used to inform an integrated thematic synthesis.

RESULTS

Fourteen studies that reported insulin experiences with 274 patients aged 60 years and over were included; nine of the studies were qualitative and five used questionnaires surveys. Seven themes emerged that were grouped into treatment-related factors (physical impact of insulin, physical capacity to administer insulin, insulin self-management behaviours) and person-centred factors (emotional factors, social factors, daily living, and personal knowledge/beliefs). Three analytical themes to guide clinical practice were derived from the data: addressing physical capacity and ability, supporting social and emotional issues and improving interactions with healthcare professionals.

CONCLUSION

The review indicates issues surrounding the technical aspects of insulin administration, side effects of treatment and reactions to insulin administration are common amongst older people. However, research evidence is limited, and there is an urgent need for empirical, participatory research with older insulin dependent adults with type 2 diabetes.

IMPLICATIONS FOR PRACTICE

Healthcare professionals need to ensure that older type 2 diabetes people on insulin are actively involved in their own care, to allow their insulin regimens to be personalised and aligned with their goals and expectations. Tailored educational interventions to reduce treatment hazards and promote physical and psychological wellbeing are also needed for this population.

摘要

背景

2型糖尿病在老年人中很常见。由于合并症和与年龄相关的残疾,尤其是在胰岛素治疗的情况下,管理老年人的糖尿病可能具有挑战性。本综述的目的是探讨老年人使用胰岛素的经历,并考虑这些经历如何为医疗服务提供信息。

综述方法

进行了一项采用主题综合法的系统综述,并根据PRISMA和ENTREQ声明进行报告。检索了1985年至2019年9月的MEDLINE、Embase、PsycInfo、CINAHL和科学网,随后在2019年12月和2022年6月进行了更新。对纳入的研究进行质量评估,将结果制成表格,并将结果用于进行综合主题综合分析。

结果

纳入了14项报告60岁及以上274名患者胰岛素使用经历的研究;其中9项研究为定性研究,5项使用问卷调查。出现了七个主题,分为与治疗相关的因素(胰岛素的身体影响、注射胰岛素的身体能力、胰岛素自我管理行为)和以患者为中心的因素(情感因素、社会因素、日常生活以及个人知识/信念)。从数据中得出了三个指导临床实践的分析主题:解决身体能力和技能问题、支持社会和情感问题以及改善与医疗保健专业人员的互动。

结论

该综述表明,胰岛素注射的技术方面、治疗副作用以及对胰岛素注射的反应等问题在老年人中很常见。然而,研究证据有限,迫切需要对2型糖尿病老年胰岛素依赖成年人进行实证性、参与性研究。

对实践的启示

医疗保健专业人员需要确保使用胰岛素的老年2型糖尿病患者积极参与自身护理,以使他们的胰岛素治疗方案个性化,并与他们的目标和期望相一致。对于这一人群,还需要量身定制的教育干预措施,以减少治疗风险并促进身心健康。

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