School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland.
The Social Insurance Institution of Finland (Kela), Research Unit, Helsinki, Finland.
Pharmacoepidemiol Drug Saf. 2023 Feb;32(2):266-276. doi: 10.1002/pds.5539. Epub 2022 Sep 21.
To study the prevalence of prescribed and over-the-counter (OTC) medicine use in children under 12 years of age in Finland and to examine factors associated with the medicine use.
A nationwide population survey was carried out in Finland in spring 2018 with a random sample of children under 12 years (n = 8000). A response rate of 24% (n = 1921) was attained. The questionnaire was sent to the child's primary guardian. Current use of prescribed medicines and the use of OTC medicines in the preceding 2 days were the main outcome measures.
Of all the children 19% had used prescribed medicines, 15% OTC medicines, and 31% either prescription or OTC medicines during the preceding 22 days. Children's health related factors were positively associated with prescribed medicine use including fairly good to poor health status, symptoms experienced, and illnesses diagnosed by a physician. The guardian's healthcare education and use of prescribed medicines were also associated with children's prescribed medicine use. Symptoms of illnesses and fairly good health status were found to be associated with childrens' use of OTC medicines.
The use of medicines in children under 12 years of age is quite common in Finland. As expected, children's health-related factors were associated with medicine use. Also, guardians' healthcare education and the use of prescribed medicines were associated with children's prescription medicine use. Children's medicine use should be continuously monitored and investigated further to identify the reasons leading to appropriate and inappropriate medicine use in children.
研究芬兰 12 岁以下儿童处方和非处方(OTC)药物使用的流行情况,并探讨与药物使用相关的因素。
2018 年春季,芬兰在全国范围内开展了一项儿童(年龄<12 岁)的随机抽样调查(n=8000)。共获得 24%的应答率(n=1921)。调查问卷由儿童的主要监护人填写。主要结局指标为当前使用处方药物和过去 2 天使用 OTC 药物的情况。
在所有儿童中,19%使用过处方药物,15%使用过 OTC 药物,31%在过去 22 天内使用过处方或 OTC 药物。儿童的健康相关因素与处方药物使用呈正相关,包括健康状况一般至较差、出现症状以及经医生诊断患有疾病。监护人的医疗保健教育程度和处方药物使用情况也与儿童处方药物使用相关。疾病症状和健康状况一般与儿童使用 OTC 药物有关。
芬兰 12 岁以下儿童使用药物的情况较为常见。与预期的一样,儿童的健康相关因素与药物使用有关。此外,监护人的医疗保健教育程度和处方药物使用情况与儿童的处方药物使用有关。应持续监测和进一步调查儿童的药物使用情况,以确定导致儿童合理和不合理用药的原因。