Ríos-Osorio Néstor, Muñoz-Alvear Hernan Darío, Jiménez-Castellanos Fabio Andrés, Quijano-Guauque Sara, Jiménez-Peña Oscar, García-Perdomo Herney Andrés, Caviedes-Bucheli Javier
Research Department COC-CICO, Institución Universitaria Colegios de Colombia UNICOC, Bogotá, Colombia.
Department of Endodontics Universidad cooperativa de Colombia, Bogotá, Colombia.
Restor Dent Endod. 2022 Jun 13;47(3):e27. doi: 10.5395/rde.2022.47.e27. eCollection 2022 Aug.
This systematic review and meta-analysis aimed to assess the association of cigarette smoking with the prevalence of post-endodontic apical periodontitis in humans.
We searched through PubMed/Medline, Web of Science, and Scopus from inception to December 2020. Risk of bias was performed by using the Newcastle-Ottawa Scale for cross-sectional, cohort, and case-control studies. We performed the statistical analysis in Review Manager 5.3 (RevMan 5.3).
6 studies met the inclusion criteria for qualitative and quantitative synthesis. Statistical analysis of these studies suggests that there were no differences in the prevalence of post endodontic apical periodontitis (AP) when comparing non-smokers smoker subjects regarding patients (odds ratio [OR], 0.68; 95% confidence interval [CI], 0.31-1.49; I2 = 58%) and teeth (OR, 1.71; 95% CI, 0.99-2.93; I2 = 72%).
Our findings suggest that there was no association between cigarette smoking and post-endodontic apical periodontitis, as we did not find statistical differences in the prevalence of post-endodontic AP when comparing non-smokers smoker subjects. Therefore, smoking should not be considered a risk factor associated with endodontic failure.
本系统评价和荟萃分析旨在评估吸烟与人类根管治疗后根尖周炎患病率之间的关联。
我们检索了从创刊至2020年12月的PubMed/Medline、科学网和Scopus数据库。采用纽卡斯尔-渥太华量表对横断面研究、队列研究和病例对照研究进行偏倚风险评估。我们使用Review Manager 5.3（RevMan 5.3）进行统计分析。
6项研究符合定性和定量综合分析的纳入标准。对这些研究的统计分析表明，在比较非吸烟者与吸烟者时，根管治疗后根尖周炎（AP）的患病率在患者方面（比值比[OR]，0.68；95%置信区间[CI]，0.31 - 1.49；I² = 58%）和牙齿方面（OR，1.71；95% CI，0.99 - 2.93；I² = 72%）均无差异。
我们的研究结果表明，吸烟与根管治疗后根尖周炎之间无关联，因为在比较非吸烟者与吸烟者时，我们未发现根管治疗后AP患病率存在统计学差异。因此，吸烟不应被视为与根管治疗失败相关的危险因素。
