Hespanhol Fernanda Garcias, Guimarães Ludmila Silva, Antunes Lívia Azeredo Alves, Antunes Leonardo Santos
Postgraduate Program, School of Dentistry, Fluminense Federal University, Niterói, RJ, Brazil.
Specific Formation Department, School of Dentistry of Nova Friburgo, Fluminense Federal University, Niterói, RJ, Brazil.
Restor Dent Endod. 2022 Jul 4;47(3):e30. doi: 10.5395/rde.2022.47.e30. eCollection 2022 Aug.
This study aimed to evaluate the effectiveness of final irrigation with cold saline solution after endodontic treatment compared with saline solution at room temperature against postoperative pain following endodontic treatment.
A broad search was performed in the PubMed, Web of Science, Scopus, Cochrane Library, Virtual Health Library (LILACS), and Grey Literature databases. Two independent reviewers performed data extraction, risk of bias using the Cochrane methodology, and certainty of evidence using the Grading of Recommendations, Assessment, Development and Evaluations (GRADE) approach.
Eight studies were included in qualitative synthesis. Intracanal cryotherapy favored the reduction of postoperative pain in the systematic review. Four studies were included in meta-analyses. The meta-analysis showed that intracanal cryotherapy reduced postoperative pain in teeth with symptomatic apical periodontitis (SAP) at 24 hours. There was no association between intracanal cryotherapy and control (room temperature) groups in teeth with normal periapical tissue with respect to postoperative pain at 24 hours and 48 hours.
Intracanal cryotherapy was effective in reducing postoperative pain after endodontic treatment in teeth with SAP.
本研究旨在评估与室温生理盐水相比，根管治疗后用冷盐水溶液进行最终冲洗对根管治疗术后疼痛的效果。
在PubMed、科学网、Scopus、Cochrane图书馆、虚拟健康图书馆（LILACS）和灰色文献数据库中进行广泛检索。两名独立的评审员进行数据提取，采用Cochrane方法评估偏倚风险，并采用推荐分级、评估、制定与评价（GRADE）方法评估证据的确定性。
八项研究纳入定性综合分析。系统评价显示根管内冷冻疗法有助于减轻术后疼痛。四项研究纳入荟萃分析。荟萃分析表明，根管内冷冻疗法可减轻有症状根尖周炎（SAP）牙齿在24小时时的术后疼痛。在根尖周组织正常的牙齿中，根管内冷冻疗法与对照组（室温）在24小时和48小时时的术后疼痛方面无关联。
根管内冷冻疗法可有效减轻SAP牙齿根管治疗后的术后疼痛。
