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重视新冠病毒感染所致疾病发病率的降低

Valuing COVID-19 Morbidity Risk Reductions.

作者信息

Robinson Lisa A, Eber Michael R, Hammitt James K

机构信息

Harvard T.H. Chan School of Public Health.

Harvard T.H. Chan School of Public Health and Harvard Graduate School of Arts and Sciences.

出版信息

J Benefit Cost Anal. 2022 Summer;13(2):247-268. doi: 10.1017/bca.2022.11. Epub 2022 Aug 3.

Abstract

Many economic analyses, including those that address the COVID-19 pandemic, focus on the value of averting deaths and do not include the value of averting nonfatal illnesses. Yet incorporating the value of averting nonfatal cases may change conclusions about the desirability of the policy. While per case values may be small, the number of nonfatal cases is often large, far outstripping the number of fatal cases. The value of averting nonfatal cases is also increasingly important in evaluating COVID-19 policy options as vaccine- and infection-related immunity and treatments reduce the case-fatality rate. Unfortunately, little valuation research is available that explicitly addresses COVID-19 morbidity. We describe and implement an approach for approximating the value of averting nonfatal illnesses or injuries and apply it to COVID-19 in the United States. We estimate gains from averting COVID-19 morbidity of about 0.01 quality-adjusted life year (QALY) per mild case averted, 0.02 QALY per severe case, and 3.15 QALYs per critical case. These gains translate into monetary values of about $5,300 per mild case, $11,000 per severe case, and $1.8 million per critical case. While these estimates are imprecise, they suggest the magnitude of the effects.

摘要

许多经济分析,包括那些针对新冠疫情的分析,都侧重于避免死亡的价值,而没有将避免非致命疾病的价值纳入其中。然而,纳入避免非致命病例的价值可能会改变有关政策可取性的结论。虽然每例的价值可能很小,但非致命病例的数量通常很大,远远超过致命病例的数量。随着疫苗和感染相关免疫力以及治疗方法降低了病死率,在评估新冠疫情政策选项时,避免非致命病例的价值也变得越来越重要。不幸的是,几乎没有明确针对新冠发病率的估值研究。我们描述并实施了一种近似估算避免非致命疾病或伤害价值的方法,并将其应用于美国的新冠疫情。我们估计,避免每例轻症新冠发病的收益约为0.01质量调整生命年(QALY),每例重症为0.02 QALY,每例危重症为3.15 QALY。这些收益转化为货币价值,每例轻症约为5300美元,每例重症约为11000美元,每例危重症约为180万美元。虽然这些估计并不精确,但它们表明了影响的规模。

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