Konietzko N
Eur J Nucl Med. 1987;13 Suppl:S16-9. doi: 10.1007/BF00253286.
Perfusion scanning of the lung is the method of choice in assessing preoperative pulmonary partial function and predicting functional operability. In addition, the quantitative perfusion scan gives an estimation of the extent of surgery. If perfusion in the tumor-affected lung is less than 30% of the total pulmonary blood flow, pneumonectomy has to be anticipated. With a perfusion of less than 10%, technical and prognostic inoperability is predicted. In M-staging, bone scanning is still the most sensitive technique available and should be used for preoperative screening, while other imaging techniques--like sonography and CT scanning--have replaced liver and brain scanning. Nuclear medicine techniques using tumoraffin substances have not achieved wide clinical application, but tumor scintigraphy with radiolabeled monoclonal tumor markers may become an important tool in the management of bronchogenic carcinoma in the near future.
肺部灌注扫描是评估术前肺部分功能和预测功能可切除性的首选方法。此外，定量灌注扫描可估计手术范围。如果患肿瘤肺的灌注小于总肺血流量的30%，则必须预期进行肺切除术。灌注小于10%时，预计技术上不可切除且预后不良。在M分期中，骨扫描仍是目前最敏感的技术，应用于术前筛查，而其他成像技术，如超声检查和CT扫描，已取代肝脏和脑部扫描。使用亲肿瘤物质的核医学技术尚未广泛应用于临床，但放射性标记单克隆肿瘤标志物的肿瘤闪烁显像在不久的将来可能成为支气管癌治疗的重要工具。
