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基于皮克林乳液法制备肉桂精油/黄原胶/壳聚糖复合微胶囊

Formation of cinnamon essential oil/xanthan gum/chitosan composite microcapsules basing on Pickering emulsions.

作者信息

Li Xin, Gao Yongfeng, Li Yaozong, Li Yanqun, Liu Haotian, Yang Zhuohong, Wu Hong, Hu Yang

机构信息

Key Laboratory for Biobased Materials and Energy of Ministry of Education, College of Materials and Energy, South China Agricultural University, Guangzhou, 510642 China.

Guangdong Key Laboratory for Innovative Development and Utilization of Forest Plant Germplasm, South China Agricultural University, Guangzhou, 510642 China.

出版信息

Colloid Polym Sci. 2022;300(10):1187-1195. doi: 10.1007/s00396-022-05019-4. Epub 2022 Sep 6.

Abstract

Cinnamon essential oil (CNO) is a natural and renewable antibacterial agent. However, CNO is highly volatile and unstable, which limits its practical application as a long-term and wide antibacterial agent. In order to improve the CNO stability, we have microencapsulated CNO into composite microcapsules basing on Pickering emulsion stabilized by silica (SiO) nanoparticles. The CNO-loaded composite microcapsules possess the hybrid microcapsule shell including SiO, xanthan gum and chitosan. Moreover, the results show that the microcapsules have spherical appearance. Microencapsulation technique effectively promotes the CNO stability, and the loaded CNO is slowly released from microcapsules. The antibacterial test indicates that the minimal inhibitory concentration of microcapsules was 2 mg mL against and , and the microcapsules can play an effective long-term antibacterial effect. Thus, Pickering emulsion templates is a convenient and effective technique to construct antibacterial essential oil-contained microcapsules, which can be used as long-term antibacterial agents.

摘要

肉桂精油(CNO)是一种天然且可再生的抗菌剂。然而,CNO具有高挥发性和不稳定性,这限制了其作为长效广谱抗菌剂的实际应用。为了提高CNO的稳定性,我们基于由二氧化硅(SiO)纳米颗粒稳定的Pickering乳液,将CNO微囊化到复合微囊中。负载CNO的复合微囊具有包含SiO、黄原胶和壳聚糖的混合微囊壳。此外,结果表明微囊呈球形外观。微囊化技术有效地提高了CNO的稳定性,负载的CNO从微囊中缓慢释放。抗菌测试表明,微囊对[具体菌种1]和[具体菌种2]的最低抑菌浓度为2 mg/mL,并且微囊可以发挥有效的长效抗菌作用。因此,Pickering乳液模板是构建含抗菌精油微囊的一种便捷有效的技术,其可作为长效抗菌剂使用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cdd9/9446719/02dc2e320c65/396_2022_5019_Fig1_HTML.jpg

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