Zhou Liquan, Cai Yahong, Li Yanjing, Zhou Yimiao, Xiao Zuowei
The First Affiliated Hospital of Hunan University of Chinese Medicine Hunan University of Chinese Medicine Changsha China.
Hunan Engineering and Technology Research Center for Health Products and Life Science, School of Pharmacy Hunan University of Chinese Medicine Changsha China.
Food Sci Nutr. 2025 Aug 29;13(9):e70814. doi: 10.1002/fsn3.70814. eCollection 2025 Sep.
Cinnamon essential oil (CEO), recognized for its broad-spectrum antimicrobial and antioxidant properties, is a natural alternative to synthetic preservatives. However, its high volatility, low water solubility, and strong odor limit direct application. This review examines advanced delivery systems-including emulsions, nanocarriers, molecular inclusion complexes, microcapsules, and liposomes-designed to enhance CEO stability, mask undesirable flavors, and enable controlled release. These systems are integrated into active, edible, and intelligent packaging forms. Active packaging extends food shelf life by inhibiting microbial growth, while intelligent packaging incorporates anthocyanin indicators for real-time freshness monitoring via pH-responsive color changes. Despite promising laboratory results, industrialization faces challenges such as high equipment costs, expensive raw materials, and stability issues. Future advancements require process optimization, low-cost carrier development, and composite material strategies to promote functional, intelligent, and scalable CEO delivery systems.
肉桂精油(CEO)以其广谱抗菌和抗氧化特性而闻名,是合成防腐剂的天然替代品。然而,其高挥发性、低水溶性和强烈气味限制了直接应用。本综述探讨了先进的递送系统,包括乳液、纳米载体、分子包合物、微胶囊和脂质体,这些系统旨在提高CEO的稳定性、掩盖不良风味并实现控释。这些系统被整合到活性、可食用和智能包装形式中。活性包装通过抑制微生物生长来延长食品保质期,而智能包装则包含花青素指示剂,通过pH响应颜色变化进行实时新鲜度监测。尽管实验室结果很有前景,但工业化面临着设备成本高、原材料昂贵和稳定性问题等挑战。未来的进展需要工艺优化、低成本载体开发和复合材料策略,以促进功能性、智能性和可扩展的CEO递送系统。